ENSDARG00000055566


Danio rerio

Features
Gene ID: ENSDARG00000055566
  
Biological name :mastl
  
Synonyms : mastl / microtubule associated serine/threonine kinase-like
  
Possible biological names infered from orthology : Q8C0P0 / Q96GX5
  
Species: Danio rerio
  
Chr. number: 24
Strand: 1
Band:
Gene start: 5893134
Gene end: 5908241
  
Corresponding Affymetrix probe sets: Dr.17720.1.A1_at (Zebrafish Array)   Dr.17720.2.S1_at (Zebrafish Array)   NM_001003609_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000072407
NCBI entrez gene - 445215     See in Manteia.
RefSeq - NM_001003609
RefSeq Peptide - NP_001003609
swissprot - F1R778
ZFIN ID - ZDB-GENE-040801-128
Ensembl - ENSDARG00000055566
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MASTLENSGALG00000007507Gallus gallus
 MASTLENSG00000120539Homo sapiens
 MastlENSMUSG00000026779Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mast2 / microtubule associated serine/threonine kinase 2 / Q6P0Q8*ENSDARG0000007431117
mast1a / microtubule associated serine/threonine kinase 1a / MAST1* / Q9R1L5* / Q9Y2H9* / microtubule associated serine/threonine kinase 1* / Microtubule-associated serine/threonine-protein...ENSDARG0000002749716
mast3b / microtubule associated serine/threonine kinase 3b / MAST3* / O60307* / Q3U214* / microtubule associated serine/threonine kinase 3* / Microtubule-associated serine/threonine-protein...ENSDARG0000008650516
mast1b / microtubule associated serine/threonine kinase 1b / MAST1* / Q9R1L5* / Q9Y2H9* / microtubule associated serine/threonine kinase 1* / Microtubule-associated serine/threonine-protein...ENSDARG0000008878916
mast3a / microtubule associated serine/threonine kinase 3a / MAST3* / O60307* / microtubule associated serine/threonine kinase 3*ENSDARG0000006172514


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
MASTL Facilitates Mitotic Progression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009323 thrombocyte thrombocyte decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000032532 arpp19a / cAMP-regulated phosphoprotein 19a / P56212* / P56211* / ARPP19* / cAMP regulated phosphoprotein 19* / Mus musculus cAMP-regulated phosphoprotein 19 (Arpp19), transcript variant 6, mRNA.*  / reaction
 ENSDARG00000039880 arpp19b / cAMP-regulated phosphoprotein 19b / P56212* / P56211* / ARPP19* / cAMP regulated phosphoprotein 19* / Mus musculus cAMP-regulated phosphoprotein 19 (Arpp19), transcript variant 6, mRNA.*  / reaction
 ENSDARG00000061644 ensab / endosulfine alpha b / ENSA* / P60840* / O43768* / endosulfine alpha* / Alpha-endosulfine *  / reaction
 ENSDARG00000036944 ensaa / Q1L8X2 / endosulfine alpha a / ENSA* / O43768* / P60840* / endosulfine alpha* / Alpha-endosulfine *  / reaction






 

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