ENSDARG00000056112


Danio rerio

Features
Gene ID: ENSDARG00000056112
  
Biological name :pikfyve
  
Synonyms : phosphoinositide kinase, FYVE finger containing / pikfyve
  
Possible biological names infered from orthology : phosphoinositide kinase, FYVE-type zinc finger containing / Q9Y2I7 / Q9Z1T6
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 32073606
Gene end: 32106034
  
Corresponding Affymetrix probe sets: Dr.2783.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000109122
Ensembl peptide - ENSDARP00000149552
Ensembl peptide - ENSDARP00000148519
Ensembl peptide - ENSDARP00000124842
Ensembl peptide - ENSDARP00000124341
Ensembl peptide - ENSDARP00000073001
Ensembl peptide - ENSDARP00000099509
Ensembl peptide - ENSDARP00000102577
NCBI entrez gene - 337690     See in Manteia.
RefSeq - NM_001127305
RefSeq - XM_005167667
RefSeq - XM_005167670
RefSeq - XM_009304725
RefSeq Peptide - NP_001120777
swissprot - F8W3P1
swissprot - B2KTE4
swissprot - B2KTE3
swissprot - B2KTE2
swissprot - B2KTE1
swissprot - F6P813
ZFIN ID - ZDB-GENE-030131-9636
Ensembl - ENSDARG00000056112
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PIKFYVEENSGALG00000008842Gallus gallus
 Q9Y2I7ENSG00000115020Homo sapiens
 Q9Z1T6ENSMUSG00000025949Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
zfyve16 / zinc finger, FYVE domain containing 16 / Q7Z3T8* / Q80U44* / zinc finger FYVE-type containing 16*ENSDARG000000757478
zfyve9a / zinc finger, FYVE domain containing 9a / ZFYVE9* / O95405* / zinc finger FYVE-type containing 9* / zinc finger, FYVE domain containing 9*ENSDARG000001019038
zfyve9b / zinc finger, FYVE domain containing 9b / ZFYVE9* / O95405* / zinc finger FYVE-type containing 9* / zinc finger, FYVE domain containing 9*ENSDARG000001007646
zfyve28 / zinc finger, FYVE domain containing 28 / Q6ZPK7* / Q9HCC9* / zinc finger FYVE-type containing 28*ENSDARG000000604304
zfyve21 / zinc finger, FYVE domain containing 21 / Q8VCM3* / Q9BQ24* / zinc finger FYVE-type containing 21*ENSDARG000000278873


Protein motifs (from Interpro)
Interpro ID Name
 IPR000306  FYVE zinc finger
 IPR000591  DEP domain
 IPR002423  Chaperonin Cpn60/TCP-1 family
 IPR002498  Phosphatidylinositol-4-phosphate 5-kinase, core
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR011991  ArsR-like helix-turn-helix domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017455  Zinc finger, FYVE-related
 IPR027409  GroEL-like apical domain superfamily
 IPR027483  Phosphatidylinositol-4-phosphate 5-kinase, C-terminal
 IPR027484  Phosphatidylinositol-4-phosphate 5-kinase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0042147 retrograde transport, endosome to Golgi IBA
 biological_processGO:0046488 phosphatidylinositol metabolic process IEA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:2000785 regulation of autophagosome assembly IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0010008 endosome membrane IBA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016307 phosphatidylinositol phosphate kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the Golgi membrane
Synthesis of PIPs at the early endosome membrane
Synthesis of PIPs at the late endosome membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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