ENSDARG00000058117


Danio rerio
membranecomplexreleasesnap25bsnaresynapticvesiclecycletargetcoiled-coilhomologydomainsnap-mitoticcytokinesislocomotorybehaviorprimingfusionpresynapticactivezoneclusteringvoltage-gatedsodiumchannelscytoplasmplasmacelljunction

Features
Gene ID: ENSDARG00000058117
  
Biological name :snap25b
  
Synonyms : Q5TZ66 / Q6PC54 / snap25a / snap25b / synaptosomal-associated protein, 25b
  
Possible biological names infered from orthology : Mus musculus synaptosomal-associated protein 25 (Snap25), transcript variant 4, mRNA. / P60879 / P60880 / SNAP25 / synaptosome associated protein 25
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 12297984
Gene end: 12389259
  
Corresponding Affymetrix probe sets: Dr.7598.1.S1_at (Zebrafish Array)   NM_131434_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000075371
Ensembl peptide - ENSDARP00000132680
Ensembl peptide - ENSDARP00000146456
NCBI entrez gene - 30711     See in Manteia.
RefSeq - NM_131434
RefSeq Peptide - NP_571509
swissprot - Q5TZ66
swissprot - Q6PC54
ZFIN ID - ZDB-GENE-980526-392
ZFIN ID - ZDB-GENE-980526-468
Ensembl - ENSDARG00000058117
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P60878ENSGALG00000009003Gallus gallus
 P60880ENSG00000132639Homo sapiens
 P60879ENSMUSG00000027273Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5TZ66 / snap25a / synaptosomal-associated protein, 25a / P60879* / SNAP25* / P60880* / synaptosome associated protein 25* / Mus musculus synaptosomal-associated protein 25 (Snap25), transc...ENSDARG0000002060990
zgc:101731ENSDARG0000004096571
snap23.1 / synaptosomal-associated protein 23.1 / O09044* / SNAP23* / O00161* / synaptosome associated protein 23* / synaptosomal-associated protein 23*ENSDARG0000001287456
snap23.2 / synaptosomal-associated protein 23.2 / O09044* / SNAP23* / O00161* / synaptosome associated protein 23* / synaptosomal-associated protein 23*ENSDARG0000005525232


Protein motifs (from Interpro)
Interpro ID Name
 IPR000727  Target SNARE coiled-coil homology domain
 IPR000928  SNAP-25


Gene Ontology (GO)
cell cyclecell divisionlocomotory behaviorcell communicationcellular component organizationcellular component biogenesisestablishment of localizationregulation of biological qualitycellular localizationanatomical structure developmentcellular developmental processdevelopmental maturationcell cyclecell divisionlocomotory behaviorcell communicationcellular component organizationcellular component biogenesisestablishment of localizationregulation of biological qualitycellular localizationanatomical structure developmentcellular developmental processdevelopmental maturationcell cyclecell divisionlocomotory behaviorcell communicationcellular component organizationcellular component biogenesisestablishment of localizationregulation of biological qualitycellular localizationanatomical structure developmentcellular developmental processdevelopmental maturationcell cyclecell divisionlocomotory behaviorcell communicationcellular component organizationcellular component biogenesisestablishment of localizationregulation of biological qualitycellular localizationanatomical structure developmentcellular developmental processdevelopmental maturationcell cyclecell divisionlocomotory behaviorcell communicationcellular component organizationcellular component biogenesisestablishment of localizationregulation of biological qualitycellular localizationanatomical structure developmentcellular developmental processdevelopmental maturationcell cyclecell divisionlocomotory behaviorcell communicationcellular component organizationcellular component biogenesisestablishment of localizationregulation of biological qualitycellular localizationanatomical structure developmentcellular developmental processdevelopmental maturationcell cyclecell divisionlocomotory behaviorcell communicationcellular component organizationcellular component biogenesisestablishment of localizationregulation of biological qualitycellular localizationanatomical structure developmentcellular developmental processdevelopmental maturationcell cyclecell divisionlocomotory behaviorcell communicationcellular component organizationcellular component biogenesisestablishment of localizationregulation of biological qualitycellular localizationanatomical structure developmentcellular developmental processdevelopmental maturationcell cyclecell divisionlocomotory behaviorcell communicationcellular component organizationcellular component biogenesisestablishment of localizationregulation of biological qualitycellular localizationanatomical structure developmentcellular developmental processdevelopmental maturationcell cyclecell divisionlocomotory behaviorcell communicationcellular component organizationcellular component biogenesisestablishment of localizationregulation of biological qualitycellular localizationanatomical structure developmentcellular developmental processdevelopmental maturationcell cyclecell cyclecell divisicell divisionlocomotory locomotory behaviorcell communcell communicationcellular cocellular component organizationcellular cocellular component biogenesisestablishmeestablishment of localizationregulation regulation of biological qualitycellular locellular localizationanatomical anatomical structure developmentcellular decellular developmental processdevelopmentdevelopmental maturation
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
cellmembranecell junctionprotein-containing complexsynapsecellmembranecell junctionprotein-containing complexsynapsecellmembranecell junctionprotein-containing complexsynapsecellmembranecell junctionprotein-containing complexsynapsecellmembranecell junctionprotein-containing complexsynapsecellmembranecell junctionprotein-containing complexsynapsecellmembranecell junctionprotein-containing complexsynapsecellmembranecell junctionprotein-containing complexsynapsecellmembranecell junctionprotein-containing complexsynapsecellmembranecell junctionprotein-containing complexsynapsecellcellmembranemembranecell junctioncell junctionprotein-containing complexprotein-containing complexsynapsesynapse
TypeGO IDTermEv.Code
 biological_processGO:0000281 mitotic cytokinesis IMP
 biological_processGO:0007626 locomotory behavior IMP
 biological_processGO:0016082 synaptic vesicle priming IBA
 biological_processGO:0031629 synaptic vesicle fusion to presynaptic active zone membrane IBA
 biological_processGO:0045162 clustering of voltage-gated sodium channels IMP
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane ISS
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031083 BLOC-1 complex ISS
 cellular_componentGO:0031201 SNARE complex ISS
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex IBA
 cellular_componentGO:0098793 presynapse IEA
 molecular_functionGO:0005484 SNAP receptor activity IBA
 molecular_functionGO:0017075 syntaxin-1 binding IBA


Pathways (from Reactome)
Pathway description
Glutamate Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Other interleukin signaling
Neutrophil degranulation
GABA synthesis, release, reuptake and degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain increased amount , abnormal
hindbrain mislocalised , abnormal
hindbrain increased distribution , abnormal
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 ZFA:0000037 anatomical structure anatomical structure increased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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