ENSDARG00000059044


Danio rerio

Features
Gene ID: ENSDARG00000059044
  
Biological name :epm2a
  
Synonyms : epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) / epm2a
  
Possible biological names infered from orthology : EPM2A, laforin glucan phosphatase / Laforin / O95278 / Q9WUA5
  
Species: Danio rerio
  
Chr. number: 23
Strand: -1
Band:
Gene start: 1526708
Gene end: 1557195
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000123332
swissprot - E9QCC5
ZFIN ID - ZDB-GENE-100922-143
Ensembl - ENSDARG00000059044
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EPM2AENSGALG00000012275Gallus gallus
 EPM2AENSG00000112425Homo sapiens
 Epm2aENSMUSG00000055493Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR002044  Carbohydrate binding module family 20
 IPR013783  Immunoglobulin-like fold
 IPR013784  Carbohydrate-binding-like fold
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR020422  Dual specificity protein phosphatase domain
 IPR024950  Dual specificity phosphatase
 IPR029021  Protein-tyrosine phosphatase-like
 IPR034831  Laforin, CBM20 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:2001070 starch binding IEA


Pathways (from Reactome)
Pathway description
Glycogen synthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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