ENSDARG00000059654


Danio rerio

Features
Gene ID: ENSDARG00000059654
  
Biological name :eif3ba
  
Synonyms : eif3ba / eukaryotic translation initiation factor 3, subunit Ba
  
Possible biological names infered from orthology : EIF3B / eukaryotic translation initiation factor 3 subunit B / P55884 / Q8JZQ9
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 41714966
Gene end: 41724932
  
Corresponding Affymetrix probe sets: Dr.6856.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000128740
NCBI entrez gene - 796380     See in Manteia.
RefSeq - NM_001290093
RefSeq Peptide - NP_001277022
swissprot - X1WET9
ZFIN ID - ZDB-GENE-030131-2748
Ensembl - ENSDARG00000059654
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EIF3BENSGALG00000040999Gallus gallus
 EIF3BENSG00000106263Homo sapiens
 Eif3bENSMUSG00000056076Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
eif3bb / eukaryotic translation initiation factor 3, subunit Bb / EIF3B* / Q8JZQ9* / P55884* / eukaryotic translation initiation factor 3 subunit B*ENSDARG0000007421386


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR011400  Eukaryotic translation initiation factor 3 subunit B
 IPR013979  Translation initiation factor, beta propellor-like domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR034363  eIF3B, RNA recognition motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001732 formation of cytoplasmic translation initiation complex IEA
 biological_processGO:0002183 cytoplasmic translational initiation IEA
 biological_processGO:0003313 heart rudiment development IMP
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation IEA
 biological_processGO:0014032 neural crest cell development IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005852 eukaryotic translation initiation factor 3 complex IEA
 cellular_componentGO:0016282 eukaryotic 43S preinitiation complex IEA
 cellular_componentGO:0033290 eukaryotic 48S preinitiation complex IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003743 translation initiation factor activity IEA
 molecular_functionGO:0031369 translation initiation factor binding IEA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000028 heart primordium heart primordium decreased size , abnormal
heart primordium decreased width , abnormal
heart primordium lacks parts or has fewer parts of type cardiac muscle cell , abnormal
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 ZFA:0000173 bulbus arteriosus bulbus arteriosus malformed , abnormal
bulbus arteriosus cylindrical , abnormal
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 ZFA:0001094 whole organism whole organism dead , abnormal
whole organism lacks parts or has fewer parts of type pharyngeal arch , abnormal
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 ZFA:0001194 cranial neural crest cranial neural crest neural crest cell development disrupted , abnormal
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 ZFA:0001655 pericardial cavity pericardial cavity edematous , abnormal
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 ZFA:0009003 cranial neural crest cell cranial neural crest cell apoptotic , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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