ENSDARG00000059817


Danio rerio

Features
Gene ID: ENSDARG00000059817
  
Biological name :mtmr12
  
Synonyms : A2BGG1 / mtmr12 / myotubularin related protein 12
  
Possible biological names infered from orthology : Mus musculus myotubularin related protein 12 (Mtmr12), transcript variant 2, mRNA. / Q80TA6 / Q9C0I1
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 41105602
Gene end: 41124241
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000077996
NCBI entrez gene - 569130     See in Manteia.
RefSeq - NM_001113613
RefSeq Peptide - NP_001107085
swissprot - A2BGG1
ZFIN ID - ZDB-GENE-050401-1
Ensembl - ENSDARG00000059817
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MTMR12ENSGALG00000003168Gallus gallus
 MTMR12ENSG00000150712Homo sapiens
 Mtmr12ENSMUSG00000039458Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mtmr10 / myotubularin related protein 10 / Q7TPM9* / Q9NXD2*ENSDARG0000001060136
mtmr11 / myotubularin related protein 11 / A4FU01* / Q3V1L6*ENSDARG0000006975514


Protein motifs (from Interpro)
Interpro ID Name
 IPR010569  Myotubularin-like phosphatase domain
 IPR011993  PH-like domain superfamily
 IPR022587  Myotubularin-related 12-like C-terminal domain
 IPR029021  Protein-tyrosine phosphatase-like
 IPR030564  Myotubularin family
 IPR030576  Myotubularin-related protein 12


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007626 locomotory behavior IMP
 biological_processGO:0048741 skeletal muscle fiber development IMP
 biological_processGO:0050790 regulation of catalytic activity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0019208 phosphatase regulator activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the early endosome membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0001094 whole organism whole organism decreased length , abnormal
whole organism decreased mobility , abnormal
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 ZFA:0001115 trunk trunk curved dorsal , abnormal
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 ZFA:0005277 skeletal muscle skeletal muscle refractivity , abnormal
skeletal muscle myofibril disorganized , abnormal
skeletal muscle sarcomere disorganized , abnormal
skeletal muscle T-tubule absent , abnormal
skeletal muscle T-tubule disorganized , abnormal
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 ZFA:0009114 muscle cell muscle cell nucleus displaced to muscle cell central region, abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000004616 mtmr2 / A0JMK5 / myotubularin related protein 2 / Q13614* / Q9Z2D1*  / complex / reaction






 

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