ENSDARG00000059836


Danio rerio
ddit3regulationrnapolymeraseiidnacomplexactivityresponsechop-atfproximalpromotersequence-specificbindingbasic-leucinezipperdomaindamage-inducibletranscripthypoxiadna-templatedlipidbiosyntheticprocessintrinsicapoptoticsignalingpathwayendoplasmicreticulum

Features
Gene ID: ENSDARG00000059836
  
Biological name :ddit3
  
Synonyms : ddit3 / DNA-damage-inducible transcript 3
  
Possible biological names infered from orthology : DNA damage-inducible transcript 3 protein / P35638 / P35639
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 58915889
Gene end: 58919086
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000078063
NCBI entrez gene - 561924     See in Manteia.
RefSeq - NM_001082825
RefSeq Peptide - NP_001076294
swissprot - F1Q964
ZFIN ID - ZDB-GENE-070410-90
Ensembl - ENSDARG00000059836
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DDIT3ENSG00000175197Homo sapiens
 Ddit3ENSMUSG00000025408Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004827  Basic-leucine zipper domain
 IPR016670  DNA damage-inducible transcript 3


Gene Ontology (GO)
response to stressresponse to abiotic stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathresponse to stressresponse to abiotic stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathresponse to stressresponse to abiotic stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathresponse to stressresponse to abiotic stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathresponse to stressresponse to abiotic stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathresponse to stressresponse to abiotic stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathresponse to stressresponse to abiotic stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathresponse to stressresponse to abiotic stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathresponse to stressresponse to abiotic stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathresponse to stressresponse to abiotic stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathresponse to stresponse to stressresponse to abresponse to abiotic stimulusnitrogen componitrogen compound metabolic processbiosynthetic pbiosynthetic processcellular metabcellular metabolic processprimary metaboprimary metabolic processorganic substaorganic substance metabolic processcell communicacell communicationcellular respocellular response to stimuluscell deathcell death
organic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityorganic cyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor acDNA-binding transcription factor activitytranscription coregulator activitytranscription coregulator activity
cellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellcellprotein-containing complexprotein-containing complexorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IDA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046890 regulation of lipid biosynthetic process IGI
 biological_processGO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IMP
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0036488 CHOP-C/EBP complex IBA
 cellular_componentGO:1990617 CHOP-ATF4 complex IBA
 cellular_componentGO:1990622 CHOP-ATF3 complex IBA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IBA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003714 transcription corepressor activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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