ENSDARG00000060165


Danio rerio

Features
Gene ID: ENSDARG00000060165
  
Biological name :dnah7
  
Synonyms : dnah7 / dynein, axonemal, heavy chain 7
  
Possible biological names infered from orthology : Dnah7a / Dnah7c / Q8WXX0
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 24951129
Gene end: 25055722
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000025608
Ensembl peptide - ENSDARP00000118929
Ensembl peptide - ENSDARP00000121407
NCBI entrez gene - 561639     See in Manteia.
RefSeq - XM_009304704
RefSeq - XM_685051
swissprot - F1Q8L1
swissprot - E9QBJ6
swissprot - F1R4M5
ZFIN ID - ZDB-GENE-070912-282
Ensembl - ENSDARG00000060165
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DNAH7ENSGALG00000007841Gallus gallus
 DNAH7ENSG00000118997Homo sapiens
 Dnah7aENSMUSG00000096141Mus musculus
 Dnah7cENSMUSG00000101337Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dnah12 / dynein, axonemal, heavy chain 12ENSDARG0000005998753
dnah3 / dynein axonemal heavy chain 3 / Q8BW94* / Dynein heavy chain 3, axonemal *ENSDARG0000006846851
dnah1 / dynein, axonemal, heavy chain 1 / E9Q8T7* / Q9P2D7* / Dynein heavy chain 1, axonemal *ENSDARG0000010011542
dnah6 / dynein, axonemal, heavy chain 6 / Q9C0G6*ENSDARG0000000060638
dnah2 / dynein, axonemal, heavy chain 2 / P0C6F1* / Q9P225* / Dynein heavy chain 2, axonemal *ENSDARG0000008735236
si:dkeyp-86b9.1 / Dnah10*ENSDARG0000006148631
dnah9l / dynein, axonemal, heavy polypeptide 9 likeENSDARG0000006263030
dnah5 / dynein, axonemal, heavy chain 5ENSDARG0000008737329
dnah11 / dynein, axonemal, heavy chain 11 / Q96DT5*ENSDARG0000009428227


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR003593  AAA+ ATPase domain
 IPR004273  Dynein heavy chain domain
 IPR013602  Dynein heavy chain, domain-2
 IPR018247  EF-Hand 1, calcium-binding site
 IPR024317  Dynein heavy chain, AAA module D4
 IPR024743  Dynein heavy chain, coiled coil stalk
 IPR026983  Dynein heavy chain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR035699  Dynein heavy chain, hydrolytic ATP-binding dynein motor region D1
 IPR035706  Dynein heavy chain, ATP-binding dynein motor region D5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003341 cilium movement IBA
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0007368 determination of left/right symmetry IMP
 biological_processGO:0036159 inner dynein arm assembly IBA
 biological_processGO:0071910 determination of liver left/right asymmetry IMP
 cellular_componentGO:0030286 dynein complex IEA
 cellular_componentGO:0036156 inner dynein arm IBA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008569 ATP-dependent microtubule motor activity, minus-end-directed IBA
 molecular_functionGO:0045503 dynein light chain binding IBA
 molecular_functionGO:0045505 dynein intermediate chain binding IBA
 molecular_functionGO:0051959 dynein light intermediate chain binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle motile cilium immobile , abnormal
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 ZFA:0000123 liver liver mislocalised , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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