ENSDARG00000061472


Danio rerio

Features
Gene ID: ENSDARG00000061472
  
Biological name :gba2
  
Synonyms : gba2 / glucosidase, beta (bile acid) 2
  
Possible biological names infered from orthology : glucosylceramidase beta 2 / Non-lysosomal glucosylceramidase / Q69ZF3 / Q9HCG7
  
Species: Danio rerio
  
Chr. number: 7
Strand: 1
Band:
Gene start: 24645186
Gene end: 24673416
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000124120
Ensembl peptide - ENSDARP00000124894
Ensembl peptide - ENSDARP00000082125
NCBI entrez gene - 559240     See in Manteia.
RefSeq - XM_005172332
swissprot - E7F5W0
swissprot - F8W4V9
swissprot - F8W624
ZFIN ID - ZDB-GENE-070522-3
Ensembl - ENSDARG00000061472
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GBA2ENSGALG00000002412Gallus gallus
 GBA2ENSG00000070610Homo sapiens
 Gba2ENSMUSG00000028467Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006775  Glycosyl-hydrolase family 116, catalytic region
 IPR008928  Six-hairpin glycosidase superfamily
 IPR014551  Beta-glucosidase GBA2-type
 IPR024462  Glycosyl-hydrolase family 116, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006680 glucosylceramide catabolic process IEA
 biological_processGO:0007409 axonogenesis IMP
 biological_processGO:0007417 central nervous system development IMP
 biological_processGO:0008152 metabolic process IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004348 glucosylceramidase activity IEA
 molecular_functionGO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds IEA
 molecular_functionGO:0008422 beta-glucosidase activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA


Pathways (from Reactome)
Pathway description
Glycosphingolipid metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000075 spinal cord spinal cord motor neuron morphology , abnormal
Show

 ZFA:0001117 post-vent region post-vent region kinked , abnormal
post-vent region shortened , abnormal
Show

 ZFA:0009248 neuron neuron axon truncated , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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