ENSDARG00000062531


Danio rerio

Features
Gene ID: ENSDARG00000062531
  
Biological name :mapk8ip3
  
Synonyms : mapk8ip3 / mitogen-activated protein kinase 8 interacting protein 3
  
Possible biological names infered from orthology : C-Jun-amino-terminal kinase-interacting protein 3 / Q9ESN9 / Q9UPT6
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 15907297
Gene end: 15988728
  
Corresponding Affymetrix probe sets: Dr.7086.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000120365
Ensembl peptide - ENSDARP00000130835
swissprot - A0A0R4IDR7
swissprot - E9QGL9
ZFIN ID - ZDB-GENE-090303-6
Ensembl - ENSDARG00000062531
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q9UPT6ENSG00000138834Homo sapiens
 Q9ESN9ENSMUSG00000024163Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
spag9a / sperm associated antigen 9a / SPAG9* / Q58A65* / O60271* / sperm associated antigen 9*ENSDARG0000007453151
SPAG9 (1 of many) / sperm associated antigen 9 / SPAG9* / O60271*ENSDARG0000007814251
si:dkey-17m8.1ENSDARG0000007953022
ARHGEF17 / si:ch211-248g20.5 / Q80U35* / Q96PE2* / Rho guanine nucleotide exchange factor 17*ENSDARG0000010164414
arhgef10la / Rho guanine nucleotide exchange factor (GEF) 10-like a / Q9HCE6* / A2AWP8* / ARHGEF10L* / Rho guanine nucleotide exchange factor 10 like* / Rho guanine nucleotide exchange fact...ENSDARG0000008863012
arhgef10 / Rho guanine nucleotide exchange factor (GEF) 10 / O15013* / Q8C033* / Rho guanine nucleotide exchange factor 10*ENSDARG0000007778811
arhgef10lb / Rho guanine nucleotide exchange factor (GEF) 10-like b / Q9HCE6* / A2AWP8* / ARHGEF10L* / Rho guanine nucleotide exchange factor 10 like* / Rho guanine nucleotide exchange fact...ENSDARG0000007424410


Protein motifs (from Interpro)
Interpro ID Name
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019143  JNK/Rab-associated protein-1, N-terminal
 IPR032486  JNK-interacting protein, leucine zipper II
 IPR034743  RH1 domain
 IPR034744  RH2 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007257 activation of JUN kinase activity IBA
 biological_processGO:0008090 retrograde axonal transport IMP
 biological_processGO:0016192 vesicle-mediated transport IBA
 biological_processGO:0046328 regulation of JNK cascade IMP
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:1904115 axon cytoplasm IEA
 molecular_functionGO:0005078 MAP-kinase scaffold activity IBA
 molecular_functionGO:0008432 JUN kinase binding IBA
 molecular_functionGO:0019894 kinesin binding IBA
 molecular_functionGO:0030159 receptor signaling complex scaffold activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system physical object quality , abnormal
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 ZFA:0000142 peripheral nervous system peripheral nervous system physical object quality , abnormal
Show

 ZFA:0000543 medial longitudinal fasciculus medial longitudinal fasciculus axon decreased length , abnormal
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 ZFA:0000944 posterior lateral line posterior lateral line lysosome mislocalised , abnormal
posterior lateral line axon decreased length , abnormal
posterior lateral line axon terminus swollen , abnormal
posterior lateral line axon terminus has extra parts of type posterior lateral line lysosome, abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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