ENSDARG00000062915


Danio rerio

Features
Gene ID: ENSDARG00000062915
  
Biological name :polr3b
  
Synonyms : polr3b / polymerase (RNA) III (DNA directed) polypeptide B
  
Possible biological names infered from orthology : DNA-directed RNA polymerase III subunit RPC2 / P59470 / Q9NW08 / RNA polymerase III subunit B
  
Species: Danio rerio
  
Chr. number: 18
Strand: -1
Band:
Gene start: 15382029
Gene end: 15420168
  
Corresponding Affymetrix probe sets: Dr.5471.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000085899
NCBI entrez gene - 562329     See in Manteia.
swissprot - F1QQA2
ZFIN ID - ZDB-GENE-030131-2887
Ensembl - ENSDARG00000062915
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 POLR3BENSGALG00000012655Gallus gallus
 POLR3BENSG00000013503Homo sapiens
 P59470ENSMUSG00000034453Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
polr2b / polymerase (RNA) II (DNA directed) polypeptide BENSDARG0000009878310


Protein motifs (from Interpro)
Interpro ID Name
 IPR007120  DNA-directed RNA polymerase, subunit 2, hybrid-binding domain
 IPR007121  RNA polymerase, beta subunit, conserved site
 IPR007641  RNA polymerase Rpb2, domain 7
 IPR007642  RNA polymerase Rpb2, domain 2
 IPR007644  RNA polymerase, beta subunit, protrusion
 IPR007645  RNA polymerase Rpb2, domain 3
 IPR007646  RNA polymerase Rpb2, domain 4
 IPR007647  RNA polymerase Rpb2, domain 5
 IPR015712  DNA-directed RNA polymerase, subunit 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006383 transcription by RNA polymerase III IEA
 biological_processGO:0009304 tRNA transcription IMP
 biological_processGO:0031017 exocrine pancreas development IMP
 biological_processGO:0048565 digestive tract development IMP
 cellular_componentGO:0005666 DNA-directed RNA polymerase III complex IBA
 molecular_functionGO:0001056 RNA polymerase III activity IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA
 molecular_functionGO:0032549 ribonucleoside binding IEA


Pathways (from Reactome)
Pathway description
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000123 liver liver decreased size , abnormal
Show

 ZFA:0000152 retina retina decreased size , abnormal
Show

 ZFA:0001155 enteric nervous system enteric nervous system complexity , abnormal
Show

 ZFA:0001249 exocrine pancreas exocrine pancreas aplastic , abnormal
exocrine pancreas decreased size , abnormal
exocrine pancreas quality , abnormal
Show

 ZFA:0001306 pharyngeal arch pharyngeal arch decreased size , abnormal
Show

 ZFA:0001338 intestine intestine decreased thickness , abnormal
intestine surface feature shape , abnormal
intestine smooth muscle contractile fiber organization quality , abnormal
intestine decreased size , abnormal
Show

 ZFA:0001439 anatomical system anatomical system quality , abnormal
Show

 ZFA:0001613 pharyngeal arch 3-7 pharyngeal arch 3-7 decreased size , abnormal
Show

 ZFA:0005124 intestinal epithelium intestinal epithelium anterior region has fewer parts of type epithelial cell microvillus, abnormal
intestinal epithelium epithelial cell cuboid , abnormal
intestinal epithelium degenerate , abnormal
intestinal epithelium positional polarity , abnormal
intestinal epithelium undifferentiated , abnormal
intestinal epithelium flat , abnormal
intestinal epithelium decreased size , abnormal
intestinal epithelium decreased thickness , abnormal
intestinal epithelium microvillus decreased size , abnormal
Show

 ZFA:0009092 exocrine cell exocrine cell undifferentiated , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr