ENSDARG00000063089


Danio rerio

Features
Gene ID: ENSDARG00000063089
  
Biological name :ccm2l
  
Synonyms : ccm2l / cerebral cavernous malformation 2-like
  
Possible biological names infered from orthology : CCM2 like scaffolding protein / Cerebral cavernous malformations 2 protein-like / Q8VCC6 / Q9NUG4
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 9035578
Gene end: 9084866
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000113989
Ensembl peptide - ENSDARP00000086332
Ensembl peptide - ENSDARP00000122837
swissprot - E7EYK9
swissprot - E9QFQ0
swissprot - F1QV14
ZFIN ID - ZDB-GENE-090313-248
Ensembl - ENSDARG00000063089
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CCM2LENSGALG00000006479Gallus gallus
 CCM2LENSG00000101331Homo sapiens
 Ccm2lENSMUSG00000027474Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ccm2 / Q6DRP4 / cerebral cavernous malformation 2 / Q8K2Y9* / Q9BSQ5* / CCM2 scaffolding protein* / Cerebral cavernous malformations *ENSDARG0000001370530


Protein motifs (from Interpro)
Interpro ID Name
 IPR011993  PH-like domain superfamily
 IPR032375  Cerebral cavernous malformations 2, harmonin-homology domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003007 heart morphogenesis IMP
 biological_processGO:0007507 heart development IMP
 biological_processGO:0009948 anterior/posterior axis specification IGI
 biological_processGO:0060047 heart contraction IGI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle increased size , abnormal
Show

 ZFA:0000114 heart heart increased size , abnormal
heart non-functional , abnormal
heart increased size , ameliorated
Show

 ZFA:0000154 sinus venosus sinus venosus dilated , abnormal
Show

 ZFA:0000471 atrium atrium dilated , abnormal
atrium increased size , abnormal
Show

 ZFA:0001094 whole organism whole organism dead , abnormal
whole organism anterior-posterior axis deformed , abnormal
whole organism anterior-posterior axis deformed , ameliorated
Show

 ZFA:0001320 endocardium endocardium dilated , abnormal
Show

 ZFA:0001655 pericardial cavity pericardial cavity increased size , abnormal
Show

 ZFA:0005035 subintestinal vein subintestinal vein disheveled , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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