ENSDARG00000068415


Danio rerio
synthaseactivityptgeslglutaredoxinglutathiones-transferasec-terminalprostaglandineelectroncellc-terminal-likeactivesitethioredoxin-likefoldtransportchainredoxhomeostasisoxidation-reductionprocesstransferproteindisulfideoxidoreductaseprostaglandin-esynthesisprostaglandinspgthromboxanes

Features
Gene ID: ENSDARG00000068415
  
Biological name :ptgesl
  
Synonyms : prostaglandin E synthase 2-like / ptgesl
  
Possible biological names infered from orthology : prostaglandin E synthase 2 / Prostaglandin E synthase 2 Prostaglandin E synthase 2 truncated form / PTGES2 / Q8BWM0 / Q9H7Z7
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 31008287
Gene end: 31013664
  
Corresponding Affymetrix probe sets: Dr.16120.1.S1_at (Zebrafish Array)   NM_200280_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000148650
Ensembl peptide - ENSDARP00000111602
NCBI entrez gene - 799964     See in Manteia.
RefSeq - NM_200280
RefSeq Peptide - NP_956574
swissprot - B0S751
ZFIN ID - ZDB-GENE-040426-1063
Ensembl - ENSDARG00000068415
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000033760Gallus gallus
 PTGES2ENSG00000148334Homo sapiens
 Ptges2ENSMUSG00000026820Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002109  Glutaredoxin
 IPR004046  Glutathione S-transferase, C-terminal
 IPR010987  Glutathione S-transferase, C-terminal-like
 IPR011767  Glutaredoxin active site
 IPR012336  Thioredoxin-like fold
 IPR034334  Prostaglandin E synthase 2
 IPR034335  Prostaglandin E synthase 2, C-terminal


Gene Ontology (GO)
cellular metabolic processoxidation-reduction processregulation of biological qualitycellular metabolic processoxidation-reduction processregulation of biological qualitycellular metabolic processoxidation-reduction processregulation of biological qualitycellular metabolic processoxidation-reduction processregulation of biological qualitycellular metabolic processoxidation-reduction processregulation of biological qualitycellular metabolic processoxidation-reduction processregulation of biological qualitycellular metabolic processoxidation-reduction processregulation of biological qualitycellular metabolic processoxidation-reduction processregulation of biological qualitycellular metabolic processoxidation-reduction processregulation of biological qualitycellular metabolic processoxidation-reduction processregulation of biological qualitycellular metabolic processcellular metabolic processoxidation-reduction processoxidation-reduction processregulation of biological qualityregulation of biological quality
oxidoreductase activityisomerase activityoxidoreductase activityisomerase activityoxidoreductase activityisomerase activityoxidoreductase activityisomerase activityoxidoreductase activityisomerase activityoxidoreductase activityisomerase activityoxidoreductase activityisomerase activityoxidoreductase activityisomerase activityoxidoreductase activityisomerase activityoxidoreductase activityisomerase activityoxidoreductase activityoxidoreductase activityisomerase activityisomerase activity
cellcellcellcellcellcellcellcellcellcellcellcell
TypeGO IDTermEv.Code
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0045454 cell redox homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005623 cell IEA
 molecular_functionGO:0009055 electron transfer activity IEA
 molecular_functionGO:0015035 protein disulfide oxidoreductase activity IEA
 molecular_functionGO:0050220 prostaglandin-E synthase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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