ENSDARG00000069893


Danio rerio

Features
Gene ID: ENSDARG00000069893
  
Biological name :sphk2
  
Synonyms : sphingosine kinase 2 / sphk2
  
Possible biological names infered from orthology : Q9JIA7 / Q9NRA0
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 32131568
Gene end: 32147182
  
Corresponding Affymetrix probe sets: Dr.12967.1.A1_at (Zebrafish Array)   Dr.15743.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000113801
Ensembl peptide - ENSDARP00000131179
NCBI entrez gene - 100150090     See in Manteia.
swissprot - A0A0R4IC42
swissprot - F1QWD8
ZFIN ID - ZDB-GENE-100922-225
Ensembl - ENSDARG00000069893
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SPHK2ENSG00000063176Homo sapiens
 Sphk2ENSMUSG00000057342Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cerk / ceramide kinase / Q8K4Q7* / Q8TCT0*ENSDARG0000006916913
zgc:158263ENSDARG0000003726712
cerkl / ceramide kinase-like / Q49MI3*ENSDARG0000007939711
agk / Q7ZW00 / acylglycerol kinase / Q53H12* / Q9ESW4* / Acylglycerol kinase, mitochondrial *ENSDARG000000098379


Protein motifs (from Interpro)
Interpro ID Name
 IPR001206  Diacylglycerol kinase, catalytic domain
 IPR016064  NAD kinase/diacylglycerol kinase-like domain superfamily
 IPR017438  Inorganic polyphosphate/ATP-NAD kinase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003007 heart morphogenesis IMP
 biological_processGO:0003318 cell migration to the midline involved in heart development IMP
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 molecular_functionGO:0003951 NAD+ kinase activity IEA
 molecular_functionGO:0016301 kinase activity IEA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000114 heart heart shape , abnormal
heart duplicated , abnormal
heart split bilaterally , abnormal
heart edematous , abnormal
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 ZFA:0000360 heart tube heart tube split bilaterally , abnormal
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 ZFA:0001117 post-vent region post-vent region epithelium blistered , abnormal
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 ZFA:0001273 ventral mandibular arch ventral mandibular arch disorganized , abnormal
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 ZFA:0005597 median fin median fin blistered , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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