ENSDARG00000070463


Danio rerio

Features
Gene ID: ENSDARG00000070463
  
Biological name :e2f3
  
Synonyms : e2f3 / E2F transcription factor 3
  
Possible biological names infered from orthology : O00716 / O35261 / Transcription factor E2F3
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 29274385
Gene end: 29294457
  
Corresponding Affymetrix probe sets: Dr.2722.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000094213
Ensembl peptide - ENSDARP00000109781
NCBI entrez gene - 791146     See in Manteia.
RefSeq - NM_001080628
RefSeq Peptide - NP_001074097
swissprot - B8JLN4
swissprot - A1L225
ZFIN ID - ZDB-GENE-070112-882
Ensembl - ENSDARG00000070463
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 E2F3ENSGALG00000012680Gallus gallus
 E2F3ENSG00000112242Homo sapiens
 E2f3ENSMUSG00000016477Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
E2F2 / si:ch211-160f23.5 / P56931* / Q14209* / E2F transcription factor 2* / Transcription factor E2F2 *ENSDARG0000007923340
e2f1 / E2F transcription factor 1 / Q01094*ENSDARG0000010386834
e2f4 / E2F transcription factor 4 / Q16254*ENSDARG0000010157824
e2f5 / E2F transcription factor 5 / Q15329* / Q61502* / Transcription factor E2F5 *ENSDARG0000003881223
si:ch211-195d17.2 / E2F6* / O54917* / O75461* / E2F transcription factor 6* / Transcription factor E2F6 *ENSDARG0000000811915


Protein motifs (from Interpro)
Interpro ID Name
 IPR003316  E2F/DP family, winged-helix DNA-binding domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR015633  E2F Family
 IPR032198  E2F transcription factor, CC-MB domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
CDC6 association with the ORC:origin complex
G2 Phase
Cyclin D associated events in G1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism increased weight , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000026577 cdk2 / cyclin-dependent kinase 2 / P24941* / P97377*  / complex / reaction
 ENSDARG00000019293 tfdp1a / transcription factor Dp-1, a / TFDP1* / TFDP3* / Q14186* / Q5H9I0* / Q08639* / transcription factor Dp-1* / transcription factor Dp family member 3*  / complex






 

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