ENSDARG00000071011


Danio rerio

Features
Gene ID: ENSDARG00000071011
  
Biological name :cdk5r2a
  
Synonyms : cdk5r2a / cyclin-dependent kinase 5, regulatory subunit 2a (p39)
  
Possible biological names infered from orthology : CDK5R2 / Cyclin-dependent kinase 5 activator 2 / cyclin dependent kinase 5 regulatory subunit 2 / O35926 / Q13319
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 13742899
Gene end: 13744681
  
Corresponding Affymetrix probe sets: Dr.6765.1.A1_at (Zebrafish Array)   NM_001017569_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000104135
NCBI entrez gene - 550231     See in Manteia.
RefSeq - NM_001017569
RefSeq Peptide - NP_001017569
swissprot - Q568S1
ZFIN ID - ZDB-GENE-050417-22
Ensembl - ENSDARG00000071011
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CDK5R2ENSGALG00000025729Gallus gallus
 CDK5R2ENSG00000171450Homo sapiens
 Cdk5r2ENSMUSG00000090071Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cdk5r2b / cyclin-dependent kinase 5, regulatory subunit 2b (p39) / Q13319* / O35926* / CDK5R2* / Cyclin-dependent kinase 5 activator 2 * / cyclin dependent kinase 5 regulatory subunit 2*ENSDARG0000007867165
cdk5r1b / cyclin-dependent kinase 5, regulatory subunit 1b (p35) / Q15078* / P61809* / CDK5R1* / cyclin dependent kinase 5 regulatory subunit 1* / Cyclin-dependent kinase 5 activator 1 Cycl...ENSDARG0000004508755
si:dkeyp-92c9.2ENSDARG0000003610554
cdk5r1a / cyclin-dependent kinase 5, regulatory subunit 1a (p35) / Q15078* / P61809* / CDK5R1* / cyclin dependent kinase 5 regulatory subunit 1* / Cyclin-dependent kinase 5 activator 1 Cycl...ENSDARG0000003791654


Protein motifs (from Interpro)
Interpro ID Name
 IPR004944  Cyclin-dependent kinase 5 activator
 IPR013763  Cyclin-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010842 retina layer formation IMP
 biological_processGO:0060059 embryonic retina morphogenesis in camera-type eye IMP
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity IEA
 cellular_componentGO:0016533 protein kinase 5 complex IEA
 molecular_functionGO:0016534 cyclin-dependent protein kinase 5 activator activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000024 retinal ganglion cell layer retinal ganglion cell layer morphology , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000152 retina retina morphology , abnormal
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 ZFA:0000435 cranial nerve II cranial nerve II decreased size , abnormal
cranial nerve II morphology , abnormal
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 ZFA:0001330 retinal outer plexiform layer retinal outer plexiform layer morphology , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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