ENSDARG00000076724


Danio rerio

Features
Gene ID: ENSDARG00000076724
  
Biological name :pi4kaa
  
Synonyms : phosphatidylinositol 4-kinase, catalytic, alpha a / pi4kaa
  
Possible biological names infered from orthology : P42356 / phosphatidylinositol 4-kinase alpha / PI4KA
  
Species: Danio rerio
  
Chr. number: 10
Strand: -1
Band:
Gene start: 3187289
Gene end: 3258073
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000100989
NCBI entrez gene - 556956     See in Manteia.
RefSeq - NM_001034972
RefSeq Peptide - NP_001030144
swissprot - F1RCP0
ZFIN ID - ZDB-GENE-100204-2
Ensembl - ENSDARG00000076724
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PI4KAENSGALG00000040756Gallus gallus
 PI4KAENSG00000241973Homo sapiens
 Pi4kaENSMUSG00000041720Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pi4kab / phosphatidylinositol 4-kinase, catalytic, alpha bENSDARG0000006282343
CABZ01065416.1ENSDARG000001149766
CABZ01065417.1ENSDARG000001167964


Protein motifs (from Interpro)
Interpro ID Name
 IPR000403  Phosphatidylinositol 3-/4-kinase, catalytic domain
 IPR001263  Phosphoinositide 3-kinase, accessory (PIK) domain
 IPR011009  Protein kinase-like domain superfamily
 IPR011989  Armadillo-like helical
 IPR015433  Phosphatidylinositol kinase
 IPR016024  Armadillo-type fold
 IPR018936  Phosphatidylinositol 3/4-kinase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030036 actin cytoskeleton organization IBA
 biological_processGO:0035118 embryonic pectoral fin morphogenesis IMP
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0048015 phosphatidylinositol-mediated signaling IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IBA
 molecular_functionGO:0004430 1-phosphatidylinositol 4-kinase activity IBA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the ER membrane
Synthesis of PIPs at the Golgi membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain necrotic , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000114 heart heart edematous , abnormal
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 ZFA:0000141 pectoral fin bud pectoral fin bud physical object quality , abnormal
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 ZFA:0001094 whole organism whole organism decreased length , abnormal
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 ZFA:0001114 head head decreased size , abnormal
head malformed , abnormal
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 ZFA:0001117 post-vent region post-vent region curved , abnormal
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 ZFA:0001161 pectoral fin pectoral fin aplastic , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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