ENSDARG00000076752


Danio rerio

Features
Gene ID: ENSDARG00000076752
  
Biological name :tmem67
  
Synonyms : tmem67 / transmembrane protein 67
  
Possible biological names infered from orthology : Q5HYA8
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 27564270
Gene end: 27581488
  
Corresponding Affymetrix probe sets: Dr.18776.1.A1_at (Zebrafish Array)   XM_695882_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000116688
NCBI entrez gene - 572194     See in Manteia.
RefSeq - XM_695882
swissprot - E9QB24
ZFIN ID - ZDB-GENE-080716-1
Ensembl - ENSDARG00000076752
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000029287Gallus gallus
 Q5HYA8ENSG00000164953Homo sapiens
 Tmem67ENSMUSG00000049488Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019170  Meckelin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003341 cilium movement IMP
 biological_processGO:0007369 gastrulation IGI
 biological_processGO:0010826 negative regulation of centrosome duplication IEA
 biological_processGO:0060027 convergent extension involved in gastrulation IGI
 biological_processGO:0060028 convergent extension involved in axis elongation IMP
 biological_processGO:0060271 cilium assembly IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0036038 MKS complex IEA


Pathways (from Reactome)
Pathway description
Anchoring of the basal body to the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain malformed , abnormal
brain hydrocephalic , abnormal
brain morphology , abnormal
brain decreased amount , abnormal
Show

 ZFA:0000029 hindbrain hindbrain hydrocephalic , abnormal
Show

 ZFA:0000107 eye eye malformed , abnormal
eye decreased size , abnormal
Show

 ZFA:0000110 fourth ventricle fourth ventricle increased size , abnormal
Show

 ZFA:0000114 heart heart edematous , abnormal
Show

 ZFA:0000135 notochord notochord increased width , abnormal
notochord malformed , abnormal
notochord undulate , abnormal
notochord morphology , abnormal
notochord kinked , abnormal
Show

 ZFA:0000138 otic placode otic placode morphology , abnormal
Show

 ZFA:0000150 pronephric duct pronephric duct cilium decreased functionality , abnormal
Show

 ZFA:0000151 pronephros pronephros cystic , abnormal
Show

 ZFA:0000155 somite somite increased width , abnormal
somite deformed , abnormal
somite morphology , abnormal
Show

 ZFA:0000217 inner ear inner ear malformed , abnormal
Show

 ZFA:0001094 whole organism whole organism increased curvature , abnormal
whole organism decreased length , abnormal
whole organism decreased thickness , abnormal
whole organism decreased life span , abnormal
whole organism anterior-posterior axis decreased length , abnormal
whole organism anterior-posterior axis shortened , abnormal
whole organism decreased amount , abnormal
Show

 ZFA:0001114 head head hydrocephalic , abnormal
head lacks parts or has fewer parts of type otic placode , abnormal
Show

 ZFA:0001117 post-vent region post-vent region malformed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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