ENSDARG00000076870


Danio rerio

Features
Gene ID: ENSDARG00000076870
  
Biological name :piezo1
  
Synonyms : piezo1 / piezo-type mechanosensitive ion channel component 1
  
Possible biological names infered from orthology : Mus musculus piezo-type mechanosensitive ion channel component 1 (Piezo1), transcript variant 1, mRNA. / Q92508
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 55328420
Gene end: 55454406
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000101429
swissprot - E7FD74
ZFIN ID - ZDB-GENE-041111-255
Ensembl - ENSDARG00000076870
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PIEZO1ENSGALG00000043725Gallus gallus
 PIEZO1ENSG00000103335Homo sapiens
 Piezo1ENSMUSG00000014444Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
piezo2a.2 / piezo-type mechanosensitive ion channel component 2a, tandem duplicate 2 / Q9H5I5* / PIEZO2* / Q8CD54* / piezo type mechanosensitive ion channel component 2*ENSDARG0000007600544
CU179656.1 / PIEZO2* / Q9H5I5* / piezo type mechanosensitive ion channel component 2*ENSDARG0000010708622
LO018508.1 / PIEZO2* / Q9H5I5* / piezo type mechanosensitive ion channel component 2*ENSDARG0000011272315
si:dkey-11f4.7ENSDARG000000992075


Protein motifs (from Interpro)
Interpro ID Name
 IPR027272  Piezo family
 IPR031334  Piezo non-specific cation channel, R-Ras-binding domain
 IPR031805  Piezo domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006884 cell volume homeostasis IMP
 biological_processGO:0034101 erythrocyte homeostasis IMP
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0042391 regulation of membrane potential IBA
 biological_processGO:0048873 homeostasis of number of cells within a tissue IMP
 biological_processGO:0050982 detection of mechanical stimulus IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071260 cellular response to mechanical stimulus IBA
 biological_processGO:0098655 cation transmembrane transport IEA
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005261 cation channel activity IBA
 molecular_functionGO:0008381 mechanosensitive ion channel activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000014 dorsal aorta dorsal aorta nucleate erythrocyte decreased amount , abnormal
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 ZFA:0000037 anatomical structure anatomical structure decreased distribution , abnormal
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 ZFA:0000105 epidermis epidermis mitotic cell cycle decreased rate , abnormal
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 ZFA:0000186 common cardinal vein common cardinal vein nucleate erythrocyte decreased amount , abnormal
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 ZFA:0000368 integument integument increased accumulation epidermal cell , abnormal
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 ZFA:0001058 caudal fin caudal fin curled , abnormal
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 ZFA:0001069 ventral fin fold ventral fin fold increased accumulation epidermal cell , abnormal
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 ZFA:0001094 whole organism whole organism monstrous , abnormal
whole organism dead , abnormal
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 ZFA:0001114 head head increased accumulation epidermal cell , abnormal
head decreased size , abnormal
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 ZFA:0009157 keratin accumulating cell keratin accumulating cell increased accumulation epidermis , abnormal
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 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte morphology , abnormal
nucleate erythrocyte increased volume , abnormal
nucleate erythrocyte spherical , abnormal
nucleate erythrocyte microtubule disorganized , abnormal
nucleate erythrocyte plasma membrane deformed , abnormal
nucleate erythrocyte deformed , abnormal
nucleate erythrocyte nucleus swollen , abnormal
nucleate erythrocyte plasma membrane broken , abnormal
nucleate erythrocyte decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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