ENSDARG00000077372


Danio rerio

Features
Gene ID: ENSDARG00000077372
  
Biological name :tfr1b
  
Synonyms : tfr1b / transferrin receptor 1b
  
Possible biological names infered from orthology : P02786 / Q62351 / TFRC / transferrin receptor
  
Species: Danio rerio
  
Chr. number: 24
Strand: 1
Band:
Gene start: 26017094
Gene end: 26031204
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000122583
NCBI entrez gene - 494478     See in Manteia.
RefSeq - NM_001009918
RefSeq Peptide - NP_001009918
swissprot - E9QGG9
ZFIN ID - ZDB-GENE-041220-2
Ensembl - ENSDARG00000077372
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TFRCENSGALG00000007485Gallus gallus
 TFRCENSG00000072274Homo sapiens
 TfrcENSMUSG00000022797Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tfr1a / transferrin receptor 1a / TFRC* / Q62351* / P02786* / transferrin receptor*ENSDARG0000010132247
tfr2 / transferrin receptor 2 / Q9UP52*ENSDARG0000010372732
si:ch211-214j8.1 / Q7M758* / Q9UQQ1* / NAALADL1* / N-acetylated alpha-linked acidic dipeptidase like 1* / N-acetylated-alpha-linked acidic dipeptidase-like protein *ENSDARG0000002095223
naalad2 / N-acetylated alpha-linked acidic dipeptidase 2 / FOLH1* / Q04609* / Q9Y3Q0* / folate hydrolase 1*ENSDARG0000002138321


Protein motifs (from Interpro)
Interpro ID Name
 IPR003137  PA domain
 IPR007365  Transferrin receptor-like, dimerisation domain
 IPR007484  Peptidase M28
 IPR029513  Transferrin receptor protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006879 cellular iron ion homeostasis IMP
 biological_processGO:0033572 transferrin transport IEA
 biological_processGO:0042541 hemoglobin biosynthetic process IMP
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0033570 transferrin transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Golgi Associated Vesicle Biogenesis
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
Transferrin endocytosis and recycling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain necrotic , abnormal
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 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0001094 whole organism whole organism viability , abnormal
whole organism decreased size , abnormal
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 ZFA:0001115 trunk trunk curved , abnormal
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 ZFA:0001117 post-vent region post-vent region curved ventral , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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