ENSDARG00000077654


Danio rerio

Features
Gene ID: ENSDARG00000077654
  
Biological name :grm8a
  
Synonyms : glutamate receptor, metabotropic 8a / grm8a
  
Possible biological names infered from orthology : glutamate metabotropic receptor 8 / glutamate receptor, metabotropic 8 / GRM8 / O00222 / P47743
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 3478049
Gene end: 3745093
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000129157
Ensembl peptide - ENSDARP00000097863
NCBI entrez gene - 792371     See in Manteia.
RefSeq - NM_001302228
RefSeq Peptide - NP_001289157
swissprot - E7FH00
swissprot - X1WG02
ZFIN ID - ZDB-GENE-110421-2
Ensembl - ENSDARG00000077654
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GRM8ENSGALG00000039403Gallus gallus
 GRM8ENSG00000179603Homo sapiens
 Grm8ENSMUSG00000024211Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
grm8b / glutamate receptor, metabotropic 8b / GRM8* / O00222* / P47743* / glutamate metabotropic receptor 8* / glutamate receptor, metabotropic 8*ENSDARG0000007650886
grm4 / glutamate receptor, metabotropic 4 / Q14833* / glutamate metabotropic receptor 4*ENSDARG0000004015671
grm6a / glutamate receptor, metabotropic 6a / GRM6* / O15303* / Q5NCH9* / glutamate metabotropic receptor 6* / Metabotropic glutamate receptor 6 *ENSDARG0000001774270
grm6b / glutamate receptor, metabotropic 6b / GRM6* / O15303* / Q5NCH9* / glutamate metabotropic receptor 6* / Metabotropic glutamate receptor 6 *ENSDARG0000002567169
FO904977.1 / GRM7* / Q14831* / glutamate metabotropic receptor 7*ENSDARG0000010026750
grm2a / glutamate receptor, metabotropic 2a / GRM2* / Q14416* / Q14BI2* / glutamate metabotropic receptor 2* / Metabotropic glutamate receptor 2 *ENSDARG0000000415044
grm3 / glutamate receptor, metabotropic 3 / Q14832* / Q9QYS2* / glutamate metabotropic receptor 3* / Metabotropic glutamate receptor 3 *ENSDARG0000003171244
grm2b / glutamate receptor, metabotropic 2b / GRM2* / Q14416* / Q14BI2* / glutamate metabotropic receptor 2* / Metabotropic glutamate receptor 2 *ENSDARG0000000719543
grm1a / glutamate receptor, metabotropic 1a / GRM1* / P97772* / Q13255* / glutamate metabotropic receptor 1* / Metabotropic glutamate receptor 1 *ENSDARG0000002679640
grm1b / glutamate receptor, metabotropic 1b / GRM1* / P97772* / Q13255* / glutamate metabotropic receptor 1* / Metabotropic glutamate receptor 1 *ENSDARG0000009832040
grm5a / glutamate receptor, metabotropic 5a / GRM5* / P41594* / glutamate metabotropic receptor 5*ENSDARG0000000444539
grm5b / glutamate receptor, metabotropic 5b / GRM5* / P41594* / glutamate metabotropic receptor 5*ENSDARG0000010206739
gprc6a / Q5U9X3 / G protein-coupled receptor, class C, group 6, member A / Q8K4Z6* / Q5T6X5* / G protein-coupled receptor, family C, group 6, member A*ENSDARG0000000537123
tas1r1 / taste receptor, type 1, member 1 / Q7RTX1* / taste 1 receptor member 1*ENSDARG0000005673921
tas1r2.1 / tas1r2.2 / taste receptor, type 1, member 2, tandem duplicate 1ENSDARG0000005313520
si:ch1073-155h21.1ENSDARG0000000758219
tas1r2.2 / taste receptor, type 1, member 2, tandem duplicate 2ENSDARG0000005939719
tas1r3 / taste receptor, type 1, member 3 / Q7RTX0* / Q925D8* / taste 1 receptor member 3*ENSDARG0000000634118
CR974456.1 / GRM7* / Q14831* / glutamate metabotropic receptor 7*ENSDARG0000011485212


Protein motifs (from Interpro)
Interpro ID Name
 IPR000144  GPCR, family 3, metabotropic glutamate receptor 8
 IPR000162  GPCR, family 3, metabotropic glutamate receptor
 IPR000337  GPCR, family 3
 IPR001786  GPCR, family 3, metabotropic glutamate receptor 4
 IPR001828  Receptor, ligand binding region
 IPR011500  GPCR, family 3, nine cysteines domain
 IPR017978  GPCR family 3, C-terminal
 IPR017979  GPCR, family 3, conserved site
 IPR028082  Periplasmic binding protein-like I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway IBA
 biological_processGO:0051966 regulation of synaptic transmission, glutamatergic IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042734 presynaptic membrane IBA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0008066 glutamate receptor activity IBA


Pathways (from Reactome)
Pathway description
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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