ENSDARG00000078979


Danio rerio

Features
Gene ID: ENSDARG00000078979
  
Biological name :arhgef40
  
Synonyms : arhgef40 / Rho guanine nucleotide exchange factor (GEF) 40
  
Possible biological names infered from orthology : Q3UPH7 / Q8TER5 / Rho guanine nucleotide exchange factor 40
  
Species: Danio rerio
  
Chr. number: 7
Strand: 1
Band:
Gene start: 73488035
Gene end: 73571518
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000099409
NCBI entrez gene - 100151026     See in Manteia.
RefSeq - XM_001919569
swissprot - E7F579
ZFIN ID - ZDB-GENE-110623-2
Ensembl - ENSDARG00000078979
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q8TER5ENSG00000165801Homo sapiens
 Q3UPH7ENSMUSG00000004562Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
plekhg4 / pleckstrin homology domain containing, family G (with RhoGef domain) member 4 / Q58EX7* / pleckstrin homology and RhoGEF domain containing G4*ENSDARG0000007596422
quo / quattro / Q5JYT7* / Q8BWG4* / KIAA1755* / D630003M21Rik* / Uncharacterized *ENSDARG0000007368420
si:dkey-65j6.2 / Q5JYT7* / Q8BWG4* / KIAA1755* / D630003M21Rik* / Uncharacterized *ENSDARG0000010358618
CABZ01053976.1 / Q5JYT7* / KIAA1755*ENSDARG000000699296
si:ch211-269k10.2 / Q5JYT7* / Q8BWG4* / KIAA1755* / D630003M21Rik* / Uncharacterized *ENSDARG000000869505


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001251  CRAL-TRIO lipid binding domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr