ENSDARG00000078992


Danio rerio

Features
Gene ID: ENSDARG00000078992
  
Biological name :wnk1a
  
Synonyms : wnk1a / WNK lysine deficient protein kinase 1a
  
Possible biological names infered from orthology : P83741 / Q9H4A3 / WNK1 / WNK lysine deficient protein kinase 1
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 21114671
Gene end: 21156678
  
Corresponding Affymetrix probe sets: Dr.2845.1.A1_at (Zebrafish Array)   Dr.2845.2.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000129163
Ensembl peptide - ENSDARP00000156107
Ensembl peptide - ENSDARP00000081066
NCBI entrez gene - 100318736     See in Manteia.
RefSeq - XM_002666846
RefSeq - XM_021470687
swissprot - E7F2F9
swissprot - X1WG08
ZFIN ID - ZDB-GENE-080917-49
Ensembl - ENSDARG00000078992
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 WNK1ENSGALG00000012992Gallus gallus
 WNK1ENSG00000060237Homo sapiens
 Wnk1ENSMUSG00000045962Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
wnk1b / WNK lysine deficient protein kinase 1b / WNK1* / Q9H4A3* / P83741* / WNK lysine deficient protein kinase 1*ENSDARG0000003939249
wnk2 / WNK lysine deficient protein kinase 2 / Q9Y3S1*ENSDARG0000010498932
wnk4b / WNK lysine deficient protein kinase 4b / WNK4* / Q96J92* / Q80UE6* / WNK lysine deficient protein kinase 4*ENSDARG0000008896728
CABZ01069040.1 / WNK3* / Q80XP9* / Q9BYP7* / WNK lysine deficient protein kinase 3*ENSDARG0000011194514
nrbp1 / nuclear receptor binding protein 1 / Q99J45* / Q9UHY1* / Mus musculus nuclear receptor binding protein 1 (Nrbp1), transcript variant 1, mRNA.*ENSDARG000000560899
nrbp2b / nuclear receptor binding protein 2b / NRBP2* / Q9NSY0* / Q91V36* / nuclear receptor binding protein 2* / Mus musculus nuclear receptor binding protein 2 (Nrbp2), transcript variant 1, mRNA.*ENSDARG000000096268
nrbp2a / nuclear receptor binding protein 2a / NRBP2* / Q9NSY0* / Q91V36* / nuclear receptor binding protein 2* / Mus musculus nuclear receptor binding protein 2 (Nrbp2), transcript variant 1, mRNA.*ENSDARG000000329518


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR024678  Serine/threonine-protein kinase OSR1/WNK, CCT domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0006468 protein phosphorylation IBA
 biological_processGO:0035556 intracellular signal transduction IBA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001057 intersegmental vein intersegmental vein decreased length , abnormal
intersegmental vein hypoplastic , abnormal
Show

 ZFA:0001267 cranial vasculature cranial vasculature aplastic , abnormal
cranial vasculature angiogenesis process quality , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel angiogenesis process quality , abnormal
Show

 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel hypoplastic , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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