ENSDARG00000079605


Danio rerio

Features
Gene ID: ENSDARG00000079605
  
Biological name :prmt5
  
Synonyms : prmt5 / protein arginine methyltransferase 5
  
Possible biological names infered from orthology : O14744 / protein arginine N-methyltransferase 5
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 38342298
Gene end: 38363017
  
Corresponding Affymetrix probe sets: Dr.5651.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000082459
NCBI entrez gene - 368664     See in Manteia.
RefSeq - NM_001007183
RefSeq Peptide - NP_001007184
swissprot - B0R026
ZFIN ID - ZDB-GENE-030616-585
Ensembl - ENSDARG00000079605
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PRMT5ENSG00000100462Homo sapiens
 Prmt5ENSMUSG00000023110Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007857  Protein arginine N-methyltransferase PRMT5
 IPR025799  Protein arginine N-methyltransferase
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase
 IPR035075  PRMT5 arginine-N-methyltransferase
 IPR035247  PRMT5, TIM barrel domain
 IPR035248  PRMT5, oligomerisation domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 biological_processGO:0006479 protein methylation IEA
 biological_processGO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine IBA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0034969 histone arginine methylation IEA
 biological_processGO:0035246 peptidyl-arginine N-methylation IEA
 biological_processGO:0048742 regulation of skeletal muscle fiber development IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008469 histone-arginine N-methyltransferase activity IEA
 molecular_functionGO:0008757 S-adenosylmethionine-dependent methyltransferase activity ISS
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
snRNP Assembly
RMTs methylate histone arginines
Regulation of TP53 Activity through Methylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000155 somite somite elongated , abnormal
somite flattened , abnormal
somite lacks parts or has fewer parts of type fast muscle cell , abnormal
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 ZFA:0001094 whole organism whole organism decreased length , abnormal
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 ZFA:0009116 slow muscle cell slow muscle cell decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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