ENSDARG00000079740


Danio rerio
ephrinefna2breceptorsignalingmembraneeph-ephrinreceptor-bindingdomaincupredoxinconservedsiteephrin-aectodomainaxonguidanceosteoclastdifferentiationboneremodelingpathwayplasmabindingepha-mediatedgrowthconecollapsemediatedrepulsioncells

Features
Gene ID: ENSDARG00000079740
  
Biological name :efna2b
  
Synonyms : efna2b / ephrin-A2b
  
Possible biological names infered from orthology : EFNA2 / ephrin A2 / O43921 / P52801
  
Species: Danio rerio
  
Chr. number: 11
Strand: 1
Band:
Gene start: 14622379
Gene end: 14640317
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000101723
swissprot - E7FB27
ZFIN ID - ZDB-GENE-141120-2
Ensembl - ENSDARG00000079740
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EFNA2ENSGALG00000038629Gallus gallus
 EFNA2ENSG00000099617Homo sapiens
 Efna2ENSMUSG00000003070Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P79727 / efna2a / ephrin-A2a / EFNA2* / O43921* / P52801* / ephrin A2*ENSDARG0000003137273
efna5a / ephrin-A5a / EFNA5* / P52803* / O08543* / ephrin A5*ENSDARG0000008979061
efna3a / ephrin-A3a / EFNA3* / O08545* / P52797* / ephrin A3* / AL691442.1*ENSDARG0000001467549
efna3b / ephrin-A3b / EFNA3* / O08545* / P52797* / ephrin A3* / AL691442.1*ENSDARG0000009829547
efna1b / ephrin-A1b / EFNA1* / P20827* / P52793* / ephrin A1* / Ephrin-A1 Ephrin-A1, secreted form*ENSDARG0000001878743
efna1a / ephrin-A1a / EFNA1* / P20827* / P52793* / ephrin A1* / Ephrin-A1 Ephrin-A1, secreted form*ENSDARG0000003032643
si:dkey-246i14.3 / EFNA4* / O08542* / P52798* / ephrin A4*ENSDARG0000009042736


Protein motifs (from Interpro)
Interpro ID Name
 IPR001799  Ephrin receptor-binding domain
 IPR008972  Cupredoxin
 IPR019765  Ephrin, conserved site
 IPR031328  Ephrin
 IPR034252  Ephrin-A ectodomain


Gene Ontology (GO)
response to external stimuluscellular component organizationresponse to chemicalmovement of cell or subcellular componentanatomical structure developmentcellular developmental processtissue remodelingcell communicationcellular response to stimulusresponse to external stimuluscellular component organizationresponse to chemicalmovement of cell or subcellular componentanatomical structure developmentcellular developmental processtissue remodelingcell communicationcellular response to stimulusresponse to external stimuluscellular component organizationresponse to chemicalmovement of cell or subcellular componentanatomical structure developmentcellular developmental processtissue remodelingcell communicationcellular response to stimulusresponse to external stimuluscellular component organizationresponse to chemicalmovement of cell or subcellular componentanatomical structure developmentcellular developmental processtissue remodelingcell communicationcellular response to stimulusresponse to external stimuluscellular component organizationresponse to chemicalmovement of cell or subcellular componentanatomical structure developmentcellular developmental processtissue remodelingcell communicationcellular response to stimulusresponse to external stimuluscellular component organizationresponse to chemicalmovement of cell or subcellular componentanatomical structure developmentcellular developmental processtissue remodelingcell communicationcellular response to stimulusresponse to external stimuluscellular component organizationresponse to chemicalmovement of cell or subcellular componentanatomical structure developmentcellular developmental processtissue remodelingcell communicationcellular response to stimulusresponse to external stimuluscellular component organizationresponse to chemicalmovement of cell or subcellular componentanatomical structure developmentcellular developmental processtissue remodelingcell communicationcellular response to stimulusresponse to external stimuluscellular component organizationresponse to chemicalmovement of cell or subcellular componentanatomical structure developmentcellular developmental processtissue remodelingcell communicationcellular response to stimulusresponse to external stimuluscellular component organizationresponse to chemicalmovement of cell or subcellular componentanatomical structure developmentcellular developmental processtissue remodelingcell communicationcellular response to stimulusresponse to extresponse to external stimuluscellular componcellular component organizationresponse to cheresponse to chemicalmovement of celmovement of cell or subcellular componentanatomical struanatomical structure developmentcellular develocellular developmental processtissue remodelitissue remodelingcell communicatcell communicationcellular responcellular response to stimulus
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
cellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellcellmembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0007411 axon guidance IBA
 biological_processGO:0030316 osteoclast differentiation IBA
 biological_processGO:0046849 bone remodeling IBA
 biological_processGO:0048013 ephrin receptor signaling pathway IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0046875 ephrin receptor binding IBA


Pathways (from Reactome)
Pathway description
EPH-Ephrin signaling
EPHA-mediated growth cone collapse
EPH-ephrin mediated repulsion of cells


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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