ENSDARG00000091756


Danio rerio

Features
Gene ID: ENSDARG00000091756
  
Biological name :insm1a
  
Synonyms : insm1a / insulinoma-associated 1a / Q6P0F9
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 48482925
Gene end: 48485354
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000107863
Ensembl peptide - ENSDARP00000124299
NCBI entrez gene - 402941     See in Manteia.
RefSeq - NM_205644
RefSeq Peptide - NP_991207
swissprot - F8W3Z6
swissprot - Q6P0F9
ZFIN ID - ZDB-GENE-040426-1810
Ensembl - ENSDARG00000091756
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
insm1b / Q7T3H2 / insulinoma-associated 1bENSDARG0000005330164
INSM2 / INSM transcriptional repressor 2 / Q96T92*ENSDARG0000002065546


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISS
 biological_processGO:0003309 type B pancreatic cell differentiation ISS
 biological_processGO:0003310 pancreatic A cell differentiation ISS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0010564 regulation of cell cycle process IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0035677 posterior lateral line neuromast hair cell development IMP
 biological_processGO:0042670 retinal cone cell differentiation IMP
 biological_processGO:0043697 cell dedifferentiation IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0048920 posterior lateral line neuromast primordium migration IMP
 biological_processGO:0060221 retinal rod cell differentiation IMP
 biological_processGO:0060290 transdifferentiation ISS
 biological_processGO:0070654 sensory epithelium regeneration IGI
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0017053 transcriptional repressor complex ISS
 molecular_functionGO:0001047 core promoter binding ISS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity ISS
 molecular_functionGO:0031490 chromatin DNA binding ISS
 molecular_functionGO:0043565 sequence-specific DNA binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000152 retina retina cell proliferative , abnormal
retina cell proliferation increased occurrence , abnormal
retina cell proliferation decreased occurrence , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased life span , abnormal
whole organism increased amount , abnormal
whole organism decreased amount , abnormal
Show

 ZFA:0001330 retinal outer plexiform layer retinal outer plexiform layer structure , abnormal
Show

 ZFA:0005179 MiP motor neuron MiP motor neuron decreased amount , abnormal
Show

 ZFA:0009243 CaP motoneuron CaP motoneuron distance CaP motoneuron , abnormal
CaP motoneuron decreased amount , abnormal
CaP motoneuron axon decreased length , abnormal
CaP motoneuron axon increased branchiness , abnormal
Show

 ZFA:0009248 neuron neuron undifferentiated , abnormal
Show

 ZFA:0009262 retinal cone cell retinal cone cell decreased amount , abnormal
Show

 ZFA:0009275 retinal rod cell retinal rod cell decreased amount , abnormal
Show

 ZFA:0009280 Muller cell Muller cell cell proliferation decreased occurrence , abnormal
Muller cell cell dedifferentiation decreased occurrence , abnormal
Show

 ZFA:0009310 retinal ganglion cell retinal ganglion cell decreased amount , abnormal
Show

 ZFA:0009315 horizontal cell horizontal cell immature , abnormal
Show

 ZFA:0009318 retinal bipolar neuron retinal bipolar neuron immature , abnormal
retinal bipolar neuron decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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