ENSDARG00000092522


Danio rerio

Features
Gene ID: ENSDARG00000092522
  
Biological name :nnt2
  
Synonyms : nicotinamide nucleotide transhydrogenase 2 / nnt2
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 18
Strand: 1
Band:
Gene start: 5543677
Gene end: 5557060
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000117906
Ensembl peptide - ENSDARP00000114052
Ensembl peptide - ENSDARP00000147982
Ensembl peptide - ENSDARP00000149489
swissprot - E9QEC6
swissprot - E9QDE7
ZFIN ID - ZDB-GENE-091204-5
Ensembl - ENSDARG00000092522
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nnt / nicotinamide nucleotide transhydrogenase / Q13423*ENSDARG0000002353675


Protein motifs (from Interpro)
Interpro ID Name
 IPR007698  Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain
 IPR007886  Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal
 IPR008143  Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2
 IPR016040  NAD(P)-binding domain
 IPR024605  NAD(P) transhydrogenase, alpha subunit, C-terminal
 IPR026255  NAD(P) transhydrogenase, alpha subunit
 IPR034300  NADP transhydrogenase beta-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006740 NADPH regeneration IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0008746 NAD(P)+ transhydrogenase activity IEA
 molecular_functionGO:0008750 NAD(P)+ transhydrogenase (AB-specific) activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0050661 NADP binding IBA
 molecular_functionGO:0051287 NAD binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle heart contraction process quality , abnormal
Show

 ZFA:0000114 heart heart edematous , abnormal
Show

 ZFA:0000471 atrium atrium increased size , abnormal
Show

 ZFA:0009316 cardiac muscle cell cardiac muscle cell cell proliferation process quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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