ENSDARG00000094729


Danio rerio

Features
Gene ID: ENSDARG00000094729
  
Biological name :apela
  
Synonyms : apela / apelin receptor early endogenous ligand / P0DMC2
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 19667947
Gene end: 19673900
  
Corresponding Affymetrix probe sets: Dr.19527.1.S1_a_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000138546
Ensembl peptide - ENSDARP00000137314
NCBI entrez gene - 100536023     See in Manteia.
RefSeq - NM_001297547
RefSeq Peptide - NP_001284476
swissprot - A0A0R4IR01
swissprot - P0DMC2
ZFIN ID - ZDB-GENE-090313-116
Ensembl - ENSDARG00000094729
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001570 vasculogenesis ISS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007369 gastrulation IEA
 biological_processGO:0007492 endoderm development IMP
 biological_processGO:0007507 heart development IMP
 biological_processGO:0007509 mesoderm migration involved in gastrulation IMP
 biological_processGO:0007512 adult heart development ISS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0035050 embryonic heart tube development ISS
 biological_processGO:0035479 angioblast cell migration from lateral mesoderm to midline IMP
 biological_processGO:0035987 endodermal cell differentiation IMP
 biological_processGO:0042074 cell migration involved in gastrulation IMP
 biological_processGO:0043009 chordate embryonic development IMP
 biological_processGO:0045766 positive regulation of angiogenesis ISS
 biological_processGO:0045823 positive regulation of heart contraction ISS
 biological_processGO:0060183 apelin receptor signaling pathway IMP
 biological_processGO:0060976 coronary vasculature development ISS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISS
 biological_processGO:0090133 mesendoderm migration IMP
 biological_processGO:0090134 cell migration involved in mesendoderm migration IMP
 biological_processGO:1901165 positive regulation of trophoblast cell migration ISS
 biological_processGO:1903589 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis ISS
 cellular_componentGO:0005576 extracellular region ISS
 cellular_componentGO:0005615 extracellular space IDA
 molecular_functionGO:0005179 hormone activity ISS
 molecular_functionGO:0031704 apelin receptor binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000017 endoderm endoderm cell migration involved in gastrulation disrupted , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000077 tail bud tail bud duplicated , abnormal
Show

 ZFA:0000106 extension extension malformed , abnormal
Show

 ZFA:0000111 germ ring germ ring constricted , abnormal
Show

 ZFA:0000114 heart heart dysplastic , abnormal
heart agenesis , abnormal
heart decreased size , abnormal
Show

 ZFA:0000117 hypoblast hypoblast movement quality , abnormal
Show

 ZFA:0000416 presumptive endoderm presumptive endoderm cell migration involved in gastrulation process quality , abnormal
Show

 ZFA:0001069 ventral fin fold ventral fin fold abnormal , abnormal
Show

 ZFA:0001094 whole organism whole organism dead , abnormal
Show

 ZFA:0001104 pharyngeal endoderm pharyngeal endoderm malformed , abnormal
Show

 ZFA:0001117 post-vent region post-vent region decreased length , abnormal
post-vent region malformed , abnormal
Show

 ZFA:0001670 notochord posterior region notochord posterior region malformed , abnormal
Show

 ZFA:0009044 blood cell blood cell increased accumulation trunk , abnormal
Show

 ZFA:0009138 mesodermal cell mesodermal cell accumulation margin , abnormal
Show

 ZFA:0009139 endodermal cell endodermal cell movement quality , abnormal
endodermal cell decreased amount , abnormal
Show

 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte increased accumulation blood island , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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