ENSDARG00000098605


Danio rerio

Features
Gene ID: ENSDARG00000098605
  
Biological name :slx1b
  
Synonyms : slx1b / SLX1 homolog B, structure-specific endonuclease subunit
  
Possible biological names infered from orthology : Q8BX32 / Q9BQ83 / SLX1A / SLX1 homolog A, structure-specific endonuclease subunit / SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 59505081
Gene end: 59515658
  
Corresponding Affymetrix probe sets: Dr.16837.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000130586
Ensembl peptide - ENSDARP00000135799
Ensembl peptide - ENSDARP00000132969
Ensembl peptide - ENSDARP00000130797
NCBI entrez gene - 100001845     See in Manteia.
RefSeq - NM_001327857
RefSeq Peptide - NP_001314786
swissprot - A0A0R4ICW7
swissprot - A0A0R4IPS6
swissprot - A0A0R4IAZ1
swissprot - A0A0R4IHC2
ZFIN ID - ZDB-GENE-130530-826
Ensembl - ENSDARG00000098605
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000044283Gallus gallus
 SLX1AENSG00000132207Homo sapiens
 SLX1BENSG00000181625Homo sapiens
 Slx1bENSMUSG00000059772Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000305  GIY-YIG endonuclease
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR027520  Structure-specific endonuclease subunit Slx1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006310 DNA recombination IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0033557 Slx1-Slx4 complex IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IEA
 molecular_functionGO:0004520 endodeoxyribonuclease activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0017108 5"-flap endonuclease activity IEA


Pathways (from Reactome)
Pathway description
Resolution of D-loop Structures through Holliday Junction Intermediates
Fanconi Anemia Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000061414 slx4 / SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae) / Q8IY92* / Q6P1D7* / SLX4 structure-specific endonuclease subunit* / Structure-specific endonuclease subunit SLX4 *  / complex
 ENSDARG00000076913 eme1 / essential meiotic structure-specific endonuclease 1 / Q8BJW7* / Q96AY2* / Crossover junction endonuclease EME1 *  / complex / reaction
 ENSDARG00000069326 mus81 / MUS81 structure-specific endonuclease subunit / Q91ZJ0* / Q96NY9* / Crossover junction endonuclease MUS81 *  / complex / reaction






 

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