ENSDARG00000098733


Danio rerio

Features
Gene ID: ENSDARG00000098733
  
Biological name :pxdn
  
Synonyms : peroxidasin / pxdn
  
Possible biological names infered from orthology : Peroxidasin homolog / Q3UQ28 / Q92626
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 51517750
Gene end: 51612088
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000149875
Ensembl peptide - ENSDARP00000152063
Ensembl peptide - ENSDARP00000131814
Ensembl peptide - ENSDARP00000148030
Ensembl peptide - ENSDARP00000148616
NCBI entrez gene - 100332937     See in Manteia.
RefSeq - XM_009293329
swissprot - A0A0G2KHM6
ZFIN ID - ZDB-GENE-140415-2
Ensembl - ENSDARG00000098733
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PXDNENSGALG00000016377Gallus gallus
 PXDNENSG00000130508Homo sapiens
 PxdnENSMUSG00000020674Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
epx / eosinophil peroxidaseENSDARG0000001253519
mpx / myeloid-specific peroxidase / MPO* / EPX* / LPO* / P49290* / P05164* / P11247* / P11678* / P22079* / lactoperoxidase* / myeloperoxidase* / eosinophil peroxidase* / Myeloperoxidase Mye...ENSDARG0000001952119


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001007  VWFC domain
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR010255  Haem peroxidase
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR019791  Haem peroxidase, animal type
 IPR032675  Leucine-rich repeat domain superfamily
 IPR034824  Peroxidasin, peroxidase domain
 IPR034828  Peroxidasin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070831 basement membrane assembly IMP
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0004601 peroxidase activity IBA
 molecular_functionGO:0020037 heme binding IEA


Pathways (from Reactome)
Pathway description
Crosslinking of collagen fibrils


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000114 heart heart edematous , abnormal
Show

 ZFA:0001094 whole organism whole organism collagen type IV trimer physical object quality , abnormal
Show

 ZFA:0001115 trunk trunk curved dorsal , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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