ENSDARG00000098883


Danio rerio

Features
Gene ID: ENSDARG00000098883
  
Biological name :stac3
  
Synonyms : Q6DBR6 / SH3 and cysteine rich domain 3 / stac3
  
Possible biological names infered from orthology : Q8BZ71 / Q96MF2 / SH3 and cysteine-rich domain-containing protein 3
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 307863
Gene end: 321351
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000147661
Ensembl peptide - ENSDARP00000151899
Ensembl peptide - ENSDARP00000131553
Ensembl peptide - ENSDARP00000133228
NCBI entrez gene - 445111     See in Manteia.
swissprot - A0A0R4IBQ8
swissprot - Q6DBR6
ZFIN ID - ZDB-GENE-040801-248
Ensembl - ENSDARG00000098883
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 STAC3ENSG00000185482Homo sapiens
 Stac3ENSMUSG00000040287Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
stac / SH3 and cysteine rich domain / P97306* / Q99469* / src homology three (SH3) and cysteine rich domain*ENSDARG0000007400431


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003009 skeletal muscle contraction IMP
 biological_processGO:0007519 skeletal muscle tissue development IMP
 biological_processGO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum IMP
 biological_processGO:0033292 T-tubule organization IMP
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:1901387 positive regulation of voltage-gated calcium channel activity ISS
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane ISS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005891 voltage-gated calcium channel complex ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane ISS
 cellular_componentGO:0042383 sarcolemma IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0005277 skeletal muscle skeletal muscle sarcoplasmic reticulum swollen , abnormal
Show

 ZFA:0009114 muscle cell muscle cell broken , abnormal
muscle cell L-type voltage-gated calcium channel complex decreased amount , abnormal
muscle cell release of sequestered calcium ion into cytosol by sarcoplasmic reticulum decreased process quality , abnormal
muscle cell L-type voltage-gated calcium channel complex structure , abnormal
muscle cell L-type voltage-gated calcium channel complex amount , ameliorated
muscle cell release of sequestered calcium ion into cytosol by sarcoplasmic reticulum process quality , ameliorated
Show

 ZFA:0009115 skeletal muscle cell skeletal muscle cell T-tubule decreased amount , abnormal
Show

 ZFA:0009116 slow muscle cell slow muscle cell morphology , abnormal
slow muscle cell decreased amount , abnormal
slow muscle cell muscle contraction process quality , abnormal
Show

 ZFA:0009117 fast muscle cell fast muscle cell muscle contraction process quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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