ENSDARG00000098916


Danio rerio

Features
Gene ID: ENSDARG00000098916
  
Biological name :krit1
  
Synonyms : krit1 / KRIT1, ankyrin repeat containing
  
Possible biological names infered from orthology : Krev interaction trapped protein 1 / O00522 / Q6S5J6
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 45991054
Gene end: 46018152
  
Corresponding Affymetrix probe sets: Dr.4553.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000138856
NCBI entrez gene - 321836     See in Manteia.
swissprot - A0A0R4IW01
ZFIN ID - ZDB-GENE-030131-555
Ensembl - ENSDARG00000098916
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KRIT1ENSGALG00000042651Gallus gallus
 KRIT1ENSG00000001631Homo sapiens
 Krit1ENSMUSG00000000600Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
frmd8 / FERM domain containing 8 / Q3UFK8* / Q9BZ67* / FERM domain-containing protein 8 *ENSDARG0000007369611


Protein motifs (from Interpro)
Interpro ID Name
 IPR002110  Ankyrin repeat
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR020683  Ankyrin repeat-containing domain
 IPR032022  KRIT, N-terminal NPxY motif-rich region


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005856 cytoskeleton IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle increased size , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000084 yolk yolk blood vessel endothelial cell increased distribution , abnormal
Show

 ZFA:0000114 heart heart increased size , abnormal
heart dilated , abnormal
heart quality , abnormal
Show

 ZFA:0000154 sinus venosus sinus venosus dilated , abnormal
Show

 ZFA:0000173 bulbus arteriosus bulbus arteriosus increased size , abnormal
Show

 ZFA:0000180 caudal vein caudal vein dilated , abnormal
caudal vein endothelial cell morphology , abnormal
caudal vein morphology , abnormal
Show

 ZFA:0000471 atrium atrium increased size , abnormal
atrium dilated , abnormal
Show

 ZFA:0000477 posterior cardinal vein posterior cardinal vein decreased thickness , abnormal
posterior cardinal vein increased diameter , abnormal
posterior cardinal vein dilated , abnormal
posterior cardinal vein endothelial cell increased distribution , abnormal
Show

 ZFA:0001057 intersegmental vein intersegmental vein unlumenized , abnormal
Show

 ZFA:0001061 intersegmental artery intersegmental artery unlumenized , abnormal
Show

 ZFA:0001078 thymus thymus decreased size , abnormal
thymus hematopoietic multipotent progenitor cell decreased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
whole organism viability , abnormal
Show

 ZFA:0001115 trunk trunk hematopoietic multipotent progenitor cell decreased amount , abnormal
Show

 ZFA:0001267 cranial vasculature cranial vasculature morphology , abnormal
cranial vasculature unlumenized , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel malformed , abnormal
intersegmental vessel unlumenized , abnormal
intersegmental vessel vacuole absent , abnormal
Show

 ZFA:0001286 caudal vein plexus caudal vein plexus sprouting angiogenesis increased occurrence , abnormal
caudal vein plexus angiogenic sprout increased amount , abnormal
caudal vein plexus morphology , abnormal
caudal vein plexus dilated , abnormal
Show

 ZFA:0001315 atrioventricular canal atrioventricular canal lacks all parts of type atrioventricular canal endocardial cushion, abnormal
atrioventricular canal endocardial cushion formation arrested , abnormal
Show

 ZFA:0001319 myocardium myocardium decreased distance endocardium , abnormal
myocardium distended , abnormal
Show

 ZFA:0001320 endocardium endocardium increased amount , abnormal
endocardium increased distribution , abnormal
Show

 ZFA:0001439 anatomical system anatomical system quality , abnormal
Show

 ZFA:0001614 atrial endocardium atrial endocardium mislocalised , abnormal
Show

 ZFA:0001615 ventricular endocardium ventricular endocardium mislocalised , abnormal
ventricular endocardium Notch signaling involved in heart development increased occurrence , abnormal
Show

 ZFA:0001616 atrioventricular canal endocardium atrioventricular canal endocardium absent , abnormal
Show

 ZFA:0001639 vascular endothelium vascular endothelium apoptotic , abnormal
Show

 ZFA:0005017 primordial midbrain channel primordial midbrain channel dilated , abnormal
Show

 ZFA:0005024 trunk vasculature trunk vasculature dilated , abnormal
Show

 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel unlumenized , abnormal
Show

 ZFA:0005035 subintestinal vein subintestinal vein increased diameter , abnormal
subintestinal vein dilated , abnormal
Show

 ZFA:0005037 post-vent vasculature post-vent vasculature morphology , abnormal
Show

 ZFA:0005054 inner optic circle inner optic circle unlumenized , abnormal
Show

 ZFA:0009036 blood vessel endothelial cell blood vessel endothelial cell decreased amount , abnormal
Show

 ZFA:0009065 endothelial cell endothelial cell increased amount , abnormal
endothelial cell increased distribution , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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