ENSDARG00000099478


Danio rerio

Features
Gene ID: ENSDARG00000099478
  
Biological name :hs2st1a
  
Synonyms : heparan sulfate 2-O-sulfotransferase 1a / hs2st1a
  
Possible biological names infered from orthology : AC093155.3 / heparan sulfate 2-O-sulfotransferase 1 / HS2ST1 / Mus musculus heparan sulfate 2-O-sulfotransferase 1 (Hs2st1), transcript variant 1, mRNA. / Q7LGA3 / Q8R3H7
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 22363824
Gene end: 22398790
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000141275
NCBI entrez gene - 791188     See in Manteia.
swissprot - A1L1P8
ZFIN ID - ZDB-GENE-070112-2312
Ensembl - ENSDARG00000099478
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HS2ST1ENSGALG00000028423Gallus gallus
 AC093155.3ENSG00000267561Homo sapiens
 HS2ST1ENSG00000153936Homo sapiens
 Hs2st1ENSMUSG00000040151Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hs2st1b / heparan sulfate 2-O-sulfotransferase 1b / Q8R3H7* / HS2ST1* / Q7LGA3* / AC093155.3* / heparan sulfate 2-O-sulfotransferase 1* / Mus musculus heparan sulfate 2-O-sulfotransferase 1...ENSDARG0000006200884
ust / uronyl-2-sulfotransferase / Q8BUB6* / Q9Y2C2*ENSDARG0000000604427
UST (1 of many) / uronyl 2-sulfotransferase / UST* / Q9Y2C2*ENSDARG0000010271527


Protein motifs (from Interpro)
Interpro ID Name
 IPR005331  Sulfotransferase
 IPR007734  Heparan sulphate 2-O-sulfotransferase
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055113 epiboly involved in gastrulation with mouth forming second IMP
 biological_processGO:0060828 regulation of canonical Wnt signaling pathway IMP
 biological_processGO:2000047 regulation of cell-cell adhesion mediated by cadherin IMP
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0008146 sulfotransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0034483 heparan sulfate sulfotransferase activity IMP


Pathways (from Reactome)
Pathway description
HS-GAG biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000086 EVL EVL cellular motility , abnormal
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 ZFA:0001094 whole organism whole organism broken , abnormal
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 ZFA:0001473 deep blastomere deep blastomere circular , abnormal
deep blastomere cellular adhesivity , abnormal
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 ZFA:0009177 blastoderm cell blastoderm cell increased size , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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