ENSDARG00000100631


Danio rerio
btbklhl12pozdomainvesiclegolgikelchrepeattypeskpsuperfamilykelch-associatedproteinmonoubiquitinationcopiicoatingmembranecopii-coatedertransportcul-ringubiquitinligasecomplexubiquitin-proteintransferaseactivitydegradationdvl

Features
Gene ID: ENSDARG00000100631
  
Biological name :klhl12
  
Synonyms : kelch-like family member 12 / klhl12
  
Possible biological names infered from orthology : Kelch-like protein 12 / Q53G59 / Q8BZM0
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 28371496
Gene end: 28383458
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000131425
swissprot - A0A0G2KGJ0
ZFIN ID - ZDB-GENE-041114-205
Ensembl - ENSDARG00000100631
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KLHL12ENSGALG00000000518Gallus gallus
 KLHL12ENSG00000117153Homo sapiens
 Klhl12ENSMUSG00000026455Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
klhl20 / kelch-like family member 20 / Q8VCK5* / Q9Y2M5* / Kelch-like protein 20 *ENSDARG0000003880147
klhl2 / kelch-like family member 2 / O95198* / Q8JZP3* / Kelch-like protein 2 *ENSDARG0000006178643
klhl17 / kelch-like family member 17 / Q6TDP3* / Q6TDP4* / Plekhn1* / Kelch-like protein 17 *ENSDARG0000003732442
klhl18 / kelch-like family member 18 / O94889*ENSDARG0000000430641
klhl3 / kelch-like family member 3 / E0CZ16* / Q9UH77* / Kelch-like protein 3 *ENSDARG0000005664741
klhl5 / kelch-like family member 5 / KLHL4* / KLHL1* / Q96PQ7* / Q9C0H6* / Q9NR64* / Q9JI74* / Kelch-like protein 1 * / kelch like family member 1* / kelch like family member 4* / kelch-lik...ENSDARG0000006212239
keap1b / kelch-like ECH-associated protein 1b / KEAP1* / Q9Z2X8* / Q14145* / kelch like ECH associated protein 1*ENSDARG0000007463433
klhl8 / kelch-like family member 8 / Q9P2G9*ENSDARG0000010127033
klhl10a / kelch-like family member 10a / Q9D5V2* / KLHL10* / Q6JEL2* / kelch-like 10* / kelch like family member 10*ENSDARG0000000581431
keap1a / kelch-like ECH-associated protein 1aENSDARG0000001613231
KLHL28 / kelch like family member 28 / Q9NXS3*ENSDARG0000010167631
klhl10b.2 / kelch-like family member 10b, tandem duplicate 2 / Q9D5V2* / KLHL10* / Q6JEL2* / kelch-like 10* / kelch like family member 10*ENSDARG0000011217031
klhl10b.1 / kelch-like family member 10b, tandem duplicate 1 / Q9D5V2* / KLHL10* / Q6JEL2* / kelch-like 10* / kelch like family member 10*ENSDARG0000011548931
KLHL12 (1 of many) / kelch like family member 12 / KLHL12* / Q53G59*ENSDARG000001127281


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated


Gene Ontology (GO)
nitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationcellular component biogenesisestablishment of localizationcellular localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationcellular component biogenesisestablishment of localizationcellular localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationcellular component biogenesisestablishment of localizationcellular localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationcellular component biogenesisestablishment of localizationcellular localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationcellular component biogenesisestablishment of localizationcellular localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationcellular component biogenesisestablishment of localizationcellular localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationcellular component biogenesisestablishment of localizationcellular localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationcellular component biogenesisestablishment of localizationcellular localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationcellular component biogenesisestablishment of localizationcellular localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationcellular component biogenesisestablishment of localizationcellular localizationnitrogen compoundnitrogen compound metabolic processcellular metabolicellular metabolic processprimary metabolicprimary metabolic processorganic substanceorganic substance metabolic processcellular componencellular component organizationcellular componencellular component biogenesisestablishment of establishment of localizationcellular localizacellular localization
catalytic activity, acting on a proteintransferase activitycatalytic activity, acting on a proteintransferase activitycatalytic activity, acting on a proteintransferase activitycatalytic activity, acting on a proteintransferase activitycatalytic activity, acting on a proteintransferase activitycatalytic activity, acting on a proteintransferase activitycatalytic activity, acting on a proteintransferase activitycatalytic activity, acting on a proteintransferase activitycatalytic activity, acting on a proteintransferase activitycatalytic activity, acting on a proteintransferase activitycatalytic activity, acting on a proteincatalytic activity, acting on a proteintransferase activitytransferase activity
cellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellcellmembranemembraneorganelleorganelleprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0006513 protein monoubiquitination IBA
 biological_processGO:0048208 COPII vesicle coating IBA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0030134 COPII-coated ER to Golgi transport vesicle IBA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA


Pathways (from Reactome)
Pathway description
Degradation of DVL


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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