ENSDARG00000100944


Danio rerio

Features
Gene ID: ENSDARG00000100944
  
Biological name :glrx2
  
Synonyms : glrx2 / glutaredoxin 2
  
Possible biological names infered from orthology : Glutaredoxin-2, mitochondrial / Q923X4 / Q9NS18
  
Species: Danio rerio
  
Chr. number: 22
Strand: 1
Band:
Gene start: 24214665
Gene end: 24219083
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000133122
Ensembl peptide - ENSDARP00000140532
Ensembl peptide - ENSDARP00000136884
NCBI entrez gene - 436677     See in Manteia.
RefSeq - XM_005161733
swissprot - A0A0R4IXU6
swissprot - A0A0R4ILJ8
swissprot - A0A0R4IFC0
ZFIN ID - ZDB-GENE-040718-101
Ensembl - ENSDARG00000100944
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GLRX2ENSGALG00000034850Gallus gallus
 GLRX2ENSG00000023572Homo sapiens
 Glrx2ENSMUSG00000018196Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002109  Glutaredoxin
 IPR011767  Glutaredoxin active site
 IPR011899  Glutaredoxin, eukaryotic/virial
 IPR012336  Thioredoxin-like fold
 IPR014025  Glutaredoxin subgroup


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001755 neural crest cell migration IMP
 biological_processGO:0001944 vasculature development IMP
 biological_processGO:0003147 neural crest cell migration involved in heart formation IMP
 biological_processGO:0007417 central nervous system development IMP
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0045454 cell redox homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0060914 heart formation IMP
 biological_processGO:0080058 protein deglutathionylation IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0009055 electron transfer activity IEA
 molecular_functionGO:0015035 protein disulfide oxidoreductase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system has fewer parts of type white matter , abnormal
central nervous system apoptotic , abnormal
Show

 ZFA:0000014 dorsal aorta dorsal aorta blood circulation decreased process quality , abnormal
Show

 ZFA:0000029 hindbrain hindbrain apoptotic , abnormal
Show

 ZFA:0000075 spinal cord spinal cord apoptotic , abnormal
Show

 ZFA:0000107 eye eye apoptotic , abnormal
Show

 ZFA:0000109 forebrain forebrain apoptotic , abnormal
Show

 ZFA:0000186 common cardinal vein common cardinal vein blood circulation decreased process quality , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel malformed , abnormal
Show

 ZFA:0005024 trunk vasculature trunk vasculature malformed , abnormal
Show

 ZFA:0009247 secondary motor neuron secondary motor neuron decreased amount , abnormal
Show

 ZFA:0009248 neuron neuron decreased amount , abnormal
neuron apoptotic , abnormal
neuron axon decreased length , abnormal
neuron axon decreased branchiness , abnormal
Show

 ZFA:0009290 glutamatergic neuron glutamatergic neuron decreased amount , abnormal
Show

 ZFA:0009301 dopaminergic neuron dopaminergic neuron decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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