ENSDARG00000101089


Danio rerio

Features
Gene ID: ENSDARG00000101089
  
Biological name :gart
  
Synonyms : gart / phosphoribosylglycinamide formyltransferase
  
Possible biological names infered from orthology : Mus musculus phosphoribosylglycinamide formyltransferase (Gart), transcript variant 2, mRNA. / P22102 / phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase / Q64737
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 960209
Gene end: 999556
  
Corresponding Affymetrix probe sets: Dr.4801.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000131447
Ensembl peptide - ENSDARP00000132785
swissprot - A0A0G2KGL2
swissprot - A0A0G2KKC3
ZFIN ID - ZDB-GENE-000616-14
Ensembl - ENSDARG00000101089
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000033199Gallus gallus
 GARTENSGALG00000037076Gallus gallus
 GARTENSG00000159131Homo sapiens
 GartENSMUSG00000022962Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000115  Phosphoribosylglycinamide synthetase
 IPR002376  Formyl transferase, N-terminal
 IPR004733  Phosphoribosylformylglycinamidine cyclo-ligase
 IPR010918  PurM-like, C-terminal domain
 IPR011054  Rudiment single hybrid motif
 IPR011761  ATP-grasp fold
 IPR013815  ATP-grasp fold, subdomain 1
 IPR016185  Pre-ATP-grasp domain superfamily
 IPR016188  PurM-like, N-terminal domain
 IPR020559  Phosphoribosylglycinamide synthetase, conserved site
 IPR020560  Phosphoribosylglycinamide synthetase, C-domain
 IPR020561  Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
 IPR020562  Phosphoribosylglycinamide synthetase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006189 "de novo" IMP biosynthetic process IEA
 biological_processGO:0009113 purine nucleobase biosynthetic process IEA
 biological_processGO:0043009 chordate embryonic development IMP
 biological_processGO:0043010 camera-type eye development IMP
 biological_processGO:0043473 pigmentation IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004637 phosphoribosylamine-glycine ligase activity IEA
 molecular_functionGO:0004641 phosphoribosylformylglycinamidine cyclo-ligase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Purine ribonucleoside monophosphate biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000144 retinal pigmented epithelium retinal pigmented epithelium quality , abnormal
retinal pigmented epithelium decreased pigmentation , abnormal
Show

 ZFA:0001094 whole organism whole organism dead , abnormal
Show

 ZFA:0001114 head head quality , abnormal
Show

 ZFA:0009091 melanocyte melanocyte pigment granule decreased amount , abnormal
Show

 ZFA:0009198 xanthophore xanthophore pigment granule decreased amount , abnormal
Show

 ZFA:0009199 iridophore iridophore pigment granule decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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