ENSDARG00000101285


Danio rerio
canapc15apccdcmediateddegradationcdhcomplexcellanaphase-promotingcycleregulationmitoticcyclinproteinslateearlyganaphasephosphorylationarmadillo-likehelicalarmadillo-typefoldsubunitdivisionspindleassemblycheckpointmolecularfunction

Features
Gene ID: ENSDARG00000101285
  
Biological name :anapc15
  
Synonyms : anapc15 / anaphase promoting complex subunit 15 / F1QY75
  
Possible biological names infered from orthology : Anapc15-ps / anaphase prompoting complex C subunit 15, pseudogene / P60006 / P60007
  
Species: Danio rerio
  
Chr. number: 15
Strand: -1
Band:
Gene start: 47334247
Gene end: 47338773
  
Corresponding Affymetrix probe sets: Dr.13292.1.S1_at (Zebrafish Array)   NM_001045450_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000139654
Ensembl peptide - ENSDARP00000143478
Ensembl peptide - ENSDARP00000148848
NCBI entrez gene - 751740     See in Manteia.
RefSeq - NM_001045450
RefSeq Peptide - NP_001038915
swissprot - F1QY75
ZFIN ID - ZDB-GENE-060825-43
Ensembl - ENSDARG00000101285
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000032499Gallus gallus
 P60006ENSG00000110200Homo sapiens
 Anapc15-psENSMUSG00000074780Mus musculus
 P60007ENSMUSG00000030649Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR026182  Anaphase-promoting complex subunit 15


Gene Ontology (GO)
cell cyclecell divisioncellular component organizationchromosome segregationcell cyclecell divisioncellular component organizationchromosome segregationcell cyclecell divisioncellular component organizationchromosome segregationcell cyclecell divisioncellular component organizationchromosome segregationcell cyclecell divisioncellular component organizationchromosome segregationcell cyclecell divisioncellular component organizationchromosome segregationcell cyclecell divisioncellular component organizationchromosome segregationcell cyclecell divisioncellular component organizationchromosome segregationcell cyclecell divisioncellular component organizationchromosome segregationcell cyclecell divisioncellular component organizationchromosome segregationcell cyclecell cyclecell divisioncell divisioncellular component organizationcellular component organizationchromosome segregationchromosome segregation
cellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellcellprotein-containing complexprotein-containing complexorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint IBA
 cellular_componentGO:0005680 anaphase-promoting complex ISS
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
CDK-mediated phosphorylation and removal of Cdc6


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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