ENSDARG00000102617


Danio rerio

Features
Gene ID: ENSDARG00000102617
  
Biological name :timp4.2
  
Synonyms : timp4.2 / TIMP metallopeptidase inhibitor 4, tandem duplicate 2
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 11
Strand: 1
Band:
Gene start: 705727
Gene end: 711032
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000134172
NCBI entrez gene - 108004535     See in Manteia.
RefSeq - NM_001328260
RefSeq Peptide - NP_001315189
swissprot - A0A0G2KP65
ZFIN ID - ZDB-GENE-160114-61
Ensembl - ENSDARG00000102617
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
timp4.3 / TIMP metallopeptidase inhibitor 4, tandem duplicate 3ENSDARG0000010079552
timp4.1 / TIMP metallopeptidase inhibitor 4, tandem duplicate 1 / TIMP4* / Q99727* / TIMP metallopeptidase inhibitor 4*ENSDARG0000011180541
timp2a / TIMP metallopeptidase inhibitor 2a / TIMP2* / P16035* / TIMP metallopeptidase inhibitor 2* / tissue inhibitor of metalloproteinase 2*ENSDARG0000006122620
timp2b / TIMP metallopeptidase inhibitor 2b / TIMP2* / P16035* / TIMP metallopeptidase inhibitor 2*ENSDARG0000007526120


Protein motifs (from Interpro)
Interpro ID Name
 IPR001134  Netrin domain
 IPR001820  Protease inhibitor I35 (TIMP)
 IPR008993  Tissue inhibitor of metalloproteinases-like, OB-fold
 IPR027465  Proteinase inhibitor I35b (TIMP), C-terminal
 IPR030490  Tissue inhibitor of metalloproteinase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009725 response to hormone IBA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0034097 response to cytokine IBA
 biological_processGO:0043086 negative regulation of catalytic activity IBA
 biological_processGO:0051045 negative regulation of membrane protein ectodomain proteolysis IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0002020 protease binding IBA
 molecular_functionGO:0008191 metalloendopeptidase inhibitor activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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