ENSDARG00000104734


Danio rerio

Features
Gene ID: ENSDARG00000104734
  
Biological name :kat2a
  
Synonyms : kat2a / K(lysine) acetyltransferase 2A
  
Possible biological names infered from orthology : lysine acetyltransferase 2A / Q92830 / Q9JHD2
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 17653784
Gene end: 17680114
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000135540
Ensembl peptide - ENSDARP00000155753
Ensembl peptide - ENSDARP00000141597
NCBI entrez gene - 555517     See in Manteia.
RefSeq - XM_009299318
swissprot - A0A0R4IXF6
swissprot - A0A0R4IN10
ZFIN ID - ZDB-GENE-080403-11
Ensembl - ENSDARG00000104734
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KAT2AENSGALG00000003369Gallus gallus
 KAT2AENSG00000108773Homo sapiens
 Kat2aENSMUSG00000020918Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
kat2b / K(lysine) acetyltransferase 2BENSDARG0000006263470
bptf / bromodomain PHD finger transcription factor / Q12830*ENSDARG0000007736123
cecr2 / cat eye syndrome chromosome region, candidate 2 / Q9BXF3* / E9Q2Z1* / Cat eye syndrome critical region * / CECR2, histone acetyl-lysine reader*ENSDARG000000783109


Protein motifs (from Interpro)
Interpro ID Name
 IPR000182  GNAT domain
 IPR001487  Bromodomain
 IPR009464  PCAF, N-terminal
 IPR016181  Acyl-CoA N-acyltransferase
 IPR016376  Histone acetyltransferase GCN5/PCAF
 IPR018359  Bromodomain, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001816 cytokine production ISS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007507 heart development IMP
 biological_processGO:0007616 long-term memory ISS
 biological_processGO:0016573 histone acetylation IEA
 biological_processGO:0018393 internal peptidyl-lysine acetylation ISS
 biological_processGO:0043966 histone H3 acetylation ISS
 biological_processGO:0045589 regulation of regulatory T cell differentiation ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0048167 regulation of synaptic plasticity ISS
 biological_processGO:0050863 regulation of T cell activation ISS
 biological_processGO:0060173 limb development IMP
 biological_processGO:0106077 histone succinylation ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome ISS
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0045252 oxoglutarate dehydrogenase complex ISS
 molecular_functionGO:0003682 chromatin binding ISS
 molecular_functionGO:0003713 transcription coactivator activity ISS
 molecular_functionGO:0004402 histone acetyltransferase activity ISS
 molecular_functionGO:0008080 N-acetyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0061733 peptide-lysine-N-acetyltransferase activity ISS
 molecular_functionGO:0106078 histone succinyltransferase activity ISS


Pathways (from Reactome)
Pathway description
B-WICH complex positively regulates rRNA expression
Ub-specific processing proteases
RUNX3 regulates NOTCH signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000068436 Q6PI20 / h3f3b.1 / H3 histone, family 3B.1 / H3F3B* / H3F3C* / P84243* / Q6NXT2* / H3 histone family member 3C* / H3 histone family member 3B*  / reaction
 ENSDARG00000105345 zgc:173552  / reaction
 ENSDARG00000105359 Q4QRF4 / FP325123.1 / Histone H3.2   / reaction






 

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