ENSDARG00000104837


Danio rerio
domainnudcheartsignalsistercshsp-likechaperonen-terminalnuclearmigrationproteinciliumassemblydeterminationleftrightasymmetryamplificationunattachedkinetochoresviamadinhibitoryseparationchromatidsresolutionchromatidcohesion

Features
Gene ID: ENSDARG00000104837
  
Biological name :nudc
  
Synonyms : nudc / nudC nuclear distribution protein
  
Possible biological names infered from orthology : nuclear distribution C, dynein complex regulator / Nuclear migration protein nudC / O35685 / Q9Y266
  
Species: Danio rerio
  
Chr. number: 19
Strand: 1
Band:
Gene start: 14158075
Gene end: 14169457
  
Corresponding Affymetrix probe sets: Dr.19967.1.S1_at (Zebrafish Array)   NM_200919_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000138015
Ensembl peptide - ENSDARP00000136053
NCBI entrez gene - 393893     See in Manteia.
RefSeq - NM_200919
RefSeq Peptide - NP_957213
swissprot - A0A0R4IR03
swissprot - Q6NV13
ZFIN ID - ZDB-GENE-040426-899
Ensembl - ENSDARG00000104837
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NUDCENSGALG00000000895Gallus gallus
 NUDCENSG00000090273Homo sapiens
 NudcENSMUSG00000028851Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nudcd3 / NudC domain containing 3 / Q8IVD9* / Q8R1N4* / NudC domain-containing protein 3 *ENSDARG0000009836124


Protein motifs (from Interpro)
Interpro ID Name
 IPR007052  CS domain
 IPR008978  HSP20-like chaperone
 IPR025934  NudC N-terminal domain
 IPR032572  Nuclear migration protein nudC


Gene Ontology (GO)
cellular component organizationcellular component biogenesisanatomical structure developmentcellular component organizationcellular component biogenesisanatomical structure developmentcellular component organizationcellular component biogenesisanatomical structure developmentcellular component organizationcellular component biogenesisanatomical structure developmentcellular component organizationcellular component biogenesisanatomical structure developmentcellular component organizationcellular component biogenesisanatomical structure developmentcellular component organizationcellular component biogenesisanatomical structure developmentcellular component organizationcellular component biogenesisanatomical structure developmentcellular component organizationcellular component biogenesisanatomical structure developmentcellular component organizationcellular component biogenesisanatomical structure developmentcellular component organizationcellular component organizationcellular component biogenesiscellular component biogenesisanatomical structure developmentanatomical structure development
TypeGO IDTermEv.Code
 biological_processGO:0060271 cilium assembly IGI
 biological_processGO:0061371 determination of heart left/right asymmetry IGI


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Telophase/Cytokinesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle cilium increased length , abnormal
Show

 ZFA:0000008 brain brain hydrocephalic , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000150 pronephric duct pronephric duct dilated , abnormal
pronephric duct cilium increased length , abnormal
pronephric duct anterior region dilated , abnormal
pronephric duct epithelial cilium movement process quality , abnormal
pronephric duct cilium disorganized , abnormal
pronephric duct cilium decreased coordination , abnormal
Show

 ZFA:0000360 heart tube heart tube mislocalised medially , abnormal
heart tube displaced to whole organism right side, abnormal
Show

 ZFA:0001094 whole organism whole organism curved , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr