ENSDARG00000110973


Danio rerio
domainadhesionactinbindingtln2blweqvinculinalpha-cateninvinculin-bindingsite-containingtalincentralcytoskeletalanchoringplasmamembranecellrufflefocalstructuralconstituentcytoskeletonfilament

Features
Gene ID: ENSDARG00000110973
  
Biological name :tln2b
  
Synonyms : talin 2b / tln2b
  
Possible biological names infered from orthology : Q9Y4G6 / talin 2 / TLN2
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 33033633
Gene end: 33151690
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000150356
Ensembl peptide - ENSDARP00000135537
Ensembl peptide - ENSDARP00000145720
Ensembl peptide - ENSDARP00000150861
Ensembl peptide - ENSDARP00000153115
swissprot - A0A0R4IID7
ZFIN ID - ZDB-GENE-130325-1
Ensembl - ENSDARG00000110973
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000029816Gallus gallus
 ENSGALG00000046618Gallus gallus
 ENSGALG00000038078Gallus gallus
 ENSGALG00000046155Gallus gallus
 ENSGALG00000003628Gallus gallus
 TLN2ENSG00000171914Homo sapiens
 Tln2ENSMUSG00000052698Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tln2a / talin 2a / TLN2* / Q9Y4G6* / talin 2*ENSDARG0000001790187
tln1 / talin 1 / P26039* / Q9Y490*ENSDARG0000010072973
hip1 / huntingtin interacting protein 1 / O00291* / Q8VD75*ENSDARG0000006297210
hip1rb / huntingtin interacting protein 1 related b / HIP1R* / O75146* / Q9JKY5* / huntingtin interacting protein 1 related* / Huntingtin-interacting protein 1-related protein *ENSDARG0000010245810
hip1ra / huntingtin interacting protein 1 related a / HIP1R* / O75146* / huntingtin interacting protein 1 related*ENSDARG000000606273
CABZ01046980.1 / TLN2* / Q9Y4G6* / talin 2*ENSDARG000001123421


Protein motifs (from Interpro)
Interpro ID Name
 IPR002558  I/LWEQ domain
 IPR006077  Vinculin/alpha-catenin
 IPR015009  Vinculin-binding site-containing domain
 IPR015224  Talin, central


Gene Ontology (GO)
cellular component organizationmacromolecule localizationregulation of biological qualitycellular localizationcell adhesioncellular component organizationmacromolecule localizationregulation of biological qualitycellular localizationcell adhesioncellular component organizationmacromolecule localizationregulation of biological qualitycellular localizationcell adhesioncellular component organizationmacromolecule localizationregulation of biological qualitycellular localizationcell adhesioncellular component organizationmacromolecule localizationregulation of biological qualitycellular localizationcell adhesioncellular component organizationmacromolecule localizationregulation of biological qualitycellular localizationcell adhesioncellular component organizationmacromolecule localizationregulation of biological qualitycellular localizationcell adhesioncellular component organizationmacromolecule localizationregulation of biological qualitycellular localizationcell adhesioncellular component organizationmacromolecule localizationregulation of biological qualitycellular localizationcell adhesioncellular component organizationmacromolecule localizationregulation of biological qualitycellular localizationcell adhesioncellular component organizatcellular component organizationmacromolecule localizationmacromolecule localizationregulation of biological quaregulation of biological qualitycellular localizationcellular localizationcell adhesioncell adhesion
protein bindingstructural constituent of cytoskeletonprotein-containing complex bindingprotein bindingstructural constituent of cytoskeletonprotein-containing complex bindingprotein bindingstructural constituent of cytoskeletonprotein-containing complex bindingprotein bindingstructural constituent of cytoskeletonprotein-containing complex bindingprotein bindingstructural constituent of cytoskeletonprotein-containing complex bindingprotein bindingstructural constituent of cytoskeletonprotein-containing complex bindingprotein bindingstructural constituent of cytoskeletonprotein-containing complex bindingprotein bindingstructural constituent of cytoskeletonprotein-containing complex bindingprotein bindingstructural constituent of cytoskeletonprotein-containing complex bindingprotein bindingstructural constituent of cytoskeletonprotein-containing complex bindingprotein bindingprotein bindingstructural constituent of cytoskeletonstructural constituent of cytoskeletonprotein-containing complex bindingprotein-containing complex binding
cellcell junctioncellcell junctioncellcell junctioncellcell junctioncellcell junctioncellcell junctioncellcell junctioncellcell junctioncellcell junctioncellcell junctioncellcellcell junctioncell junction
TypeGO IDTermEv.Code
 biological_processGO:0007016 cytoskeletal anchoring at plasma membrane IEA
 biological_processGO:0007155 cell adhesion IEA
 cellular_componentGO:0001726 ruffle IEA
 cellular_componentGO:0005925 focal adhesion IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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