ENSG00000004779


Homo sapiens

Features
Gene ID: ENSG00000004779
  
Biological name :NDUFAB1
  
Synonyms : NADH:ubiquinone oxidoreductase subunit AB1 / NDUFAB1 / O14561
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: p12.2
Gene start: 23581002
Gene end: 23596356
  
Corresponding Affymetrix probe sets: 202077_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000454812
Ensembl peptide - ENSP00000458770
Ensembl peptide - ENSP00000461693
Ensembl peptide - ENSP00000007516
Ensembl peptide - ENSP00000454891
NCBI entrez gene - 4706     See in Manteia.
OMIM - 603836
RefSeq - XM_011545856
RefSeq - NM_005003
RefSeq Peptide - NP_004994
swissprot - I3L505
swissprot - H3BNE8
swissprot - O14561
swissprot - H3BNK3
Ensembl - ENSG00000004779
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ndufab1aENSDARG00000058463Danio rerio
 ndufab1bENSDARG00000014915Danio rerio
 NDUFAB1ENSGALG00000006073Gallus gallus
 Q9CR21ENSMUSG00000030869Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003231  Acyl carrier protein (ACP)
 IPR006162  Phosphopantetheine attachment site
 IPR009081  Phosphopantetheine binding ACP domain
 IPR036736  ACP-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006120 mitochondrial electron transport, NADH to ubiquinone TAS
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 biological_processGO:0006635 fatty acid beta-oxidation TAS
 biological_processGO:0009245 lipid A biosynthetic process IBA
 biological_processGO:0009249 protein lipoylation IMP
 biological_processGO:0032981 mitochondrial respiratory chain complex I assembly TAS
 biological_processGO:0034641 cellular nitrogen compound metabolic process TAS
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane TAS
 cellular_componentGO:0005747 mitochondrial respiratory chain complex I NAS
 cellular_componentGO:0005759 mitochondrial matrix ISS
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0031966 mitochondrial membrane NAS
 cellular_componentGO:0070469 respiratory chain IEA
 molecular_functionGO:0000035 acyl binding IBA
 molecular_functionGO:0000036 acyl carrier activity NAS
 molecular_functionGO:0005504 fatty acid binding ISS
 molecular_functionGO:0005509 calcium ion binding NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008137 NADH dehydrogenase (ubiquinone) activity NAS
 molecular_functionGO:0031177 phosphopantetheine binding IBA


Pathways (from Reactome)
Pathway description
Glyoxylate metabolism and glycine degradation
Respiratory electron transport
Complex I biogenesis
Mitochondrial Fatty Acid Beta-Oxidation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000140905 GCSH / P23434 / glycine cleavage system protein H  / reaction
 ENSG00000100294 MCAT / Q8IVS2 / malonyl-CoA-acyl carrier protein transacylase  / reaction






 

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