ENSG00000021645


Homo sapiens

Features
Gene ID: ENSG00000021645
  
Biological name :NRXN3
  
Synonyms : neurexin 3 / NRXN3 / Q9HDB5 / Q9Y4C0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q24.3
Gene start: 78170373
Gene end: 79868290
  
Corresponding Affymetrix probe sets: 205795_at (Human Genome U133 Plus 2.0 Array)   215020_at (Human Genome U133 Plus 2.0 Array)   215021_s_at (Human Genome U133 Plus 2.0 Array)   229649_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000451672
Ensembl peptide - ENSP00000451648
Ensembl peptide - ENSP00000451754
Ensembl peptide - ENSP00000489551
Ensembl peptide - ENSP00000488920
Ensembl peptide - ENSP00000451947
Ensembl peptide - ENSP00000281127
Ensembl peptide - ENSP00000338349
Ensembl peptide - ENSP00000394426
Ensembl peptide - ENSP00000450462
Ensembl peptide - ENSP00000450683
Ensembl peptide - ENSP00000451393
NCBI entrez gene - 9369     See in Manteia.
OMIM - 600567
RefSeq - XM_017021807
RefSeq - XM_017021793
RefSeq - XM_017021794
RefSeq - XM_017021795
RefSeq - XM_017021796
RefSeq - XM_017021797
RefSeq - XM_017021798
RefSeq - XM_017021799
RefSeq - XM_017021800
RefSeq - XM_017021801
RefSeq - XM_017021802
RefSeq - XM_017021803
RefSeq - XM_017021804
RefSeq - XM_017021805
RefSeq - XM_017021806
RefSeq - NM_001105250
RefSeq - NM_001272020
RefSeq - NM_004796
RefSeq - NM_138970
RefSeq - XM_005268218
RefSeq - XM_006720322
RefSeq - XM_006720323
RefSeq - XM_011537363
RefSeq - XM_011537364
RefSeq - XM_011537365
RefSeq - XM_011537366
RefSeq - XM_011537367
RefSeq - XM_011537368
RefSeq - XM_011537369
RefSeq - XM_011537370
RefSeq - XM_011537371
RefSeq - XM_011537372
RefSeq - XM_011537373
RefSeq - XM_011537377
RefSeq - XM_017021790
RefSeq - XM_017021791
RefSeq - XM_017021792
RefSeq Peptide - NP_620426
RefSeq Peptide - NP_001098720
RefSeq Peptide - NP_001258949
RefSeq Peptide - NP_001317124
RefSeq Peptide - NP_004787
swissprot - H0YJL2
swissprot - A0A0U1RRJ0
swissprot - Q9Y4C0
swissprot - A0A0A0MR89
swissprot - Q9HDB5
swissprot - A0A0U1RQC5
swissprot - A0A0C4DGK4
swissprot - G3V247
swissprot - G3V4R9
Ensembl - ENSG00000021645
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nrxn3aENSDARG00000043746Danio rerio
 nrxn3bENSDARG00000062693Danio rerio
 NRXN3ENSGALG00000010518Gallus gallus
 Nrxn3ENSMUSG00000066392Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NRXN2 / P58401 / Q9P2S2 / neurexin 2ENSG0000011007666
NRXN1 / P58400 / Q9ULB1 / neurexin 1ENSG0000017991566
Q9C0A0 / CNTNAP4 / contactin associated protein like 4ENSG0000015291019
Q8WYK1 / CNTNAP5 / contactin associated protein like 5ENSG0000015505219
Q9UHC6 / CNTNAP2 / contactin associated protein like 2ENSG0000017446919
Q9BZ76 / CNTNAP3 / contactin associated protein like 3ENSG0000010671418
Q96NU0 / CNTNAP3B / contactin associated protein like 3BENSG0000015452918
P78357 / CNTNAP1 / contactin associated protein 1ENSG0000010879717
BX088645.1ENSG000002833787
AC104151.1ENSG000002618331


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001791  Laminin G domain
 IPR003585  Neurexin/syndecan/glycophorin C
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR027789  Syndecan/Neurexin domain
 IPR037440  Neurexin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis ISS
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007158 neuron cell-cell adhesion TAS
 biological_processGO:0007165 signal transduction NAS
 biological_processGO:0007268 chemical synaptic transmission IEA
 biological_processGO:0007269 neurotransmitter secretion IEA
 biological_processGO:0007411 axon guidance TAS
 biological_processGO:0007416 synapse assembly IEA
 biological_processGO:0007612 learning IGI
 biological_processGO:0030534 adult behavior IGI
 biological_processGO:0035176 social behavior IGI
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0071625 vocalization behavior IGI
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0098793 presynapse IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity NAS
 molecular_functionGO:0005246 calcium channel regulator activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050839 cell adhesion molecule binding TAS
 molecular_functionGO:0097109 neuroligin family protein binding TAS


Pathways (from Reactome)
Pathway description
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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