ENSG00000023697


Homo sapiens
catabolicprocessDERAaldolaseactivityneutrophildegranulationphosphateextracellulargranulelumendeocfbablacdaldolase-typetimbarrelpentose-phosphateshuntdeoxyribonucleotidecarbohydratedeoxyribonucleosidedeoxyriboseregionnucleuscytoplasmcytosolsecretoryexosomeficolin-

Features
Gene ID: ENSG00000023697
  
Biological name :DERA
  
Synonyms : deoxyribose-phosphate aldolase / DERA / Q9Y315
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: p12.3
Gene start: 15911172
Gene end: 16037282
  
Corresponding Affymetrix probe sets: 218102_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000431757
Ensembl peptide - ENSP00000436999
Ensembl peptide - ENSP00000435683
Ensembl peptide - ENSP00000434973
Ensembl peptide - ENSP00000433801
Ensembl peptide - ENSP00000433051
Ensembl peptide - ENSP00000432633
Ensembl peptide - ENSP00000416583
NCBI entrez gene - 51071     See in Manteia.
RefSeq - NM_015954
RefSeq - NM_001300779
RefSeq Peptide - NP_001287708
RefSeq Peptide - NP_057038
swissprot - E9PJB9
swissprot - E9PJ44
swissprot - G3V158
swissprot - E9PPM8
swissprot - Q9Y315
swissprot - E9PPK3
swissprot - E9PML7
swissprot - E9PMH9
Ensembl - ENSG00000023697
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 deraENSDARG00000005897Danio rerio
 DERAENSGALG00000013095Gallus gallus
 DeraENSMUSG00000030225Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002915  DeoC/FbaB/ lacD aldolase
 IPR011343  Deoxyribose-phosphate aldolase
 IPR013785  Aldolase-type TIM barrel


Gene Ontology (GO)
nitrogen compound metabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processcatabolic processimmune responseestablishment of localizationcell activationimmune effector processnitrogen compound metabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processcatabolic processimmune responseestablishment of localizationcell activationimmune effector processnitrogen compound metabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processcatabolic processimmune responseestablishment of localizationcell activationimmune effector processnitrogen compound metabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processcatabolic processimmune responseestablishment of localizationcell activationimmune effector processnitrogen compound metabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processcatabolic processimmune responseestablishment of localizationcell activationimmune effector processnitrogen compound metabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processcatabolic processimmune responseestablishment of localizationcell activationimmune effector processnitrogen compound metabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processcatabolic processimmune responseestablishment of localizationcell activationimmune effector processnitrogen compound metabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processcatabolic processimmune responseestablishment of localizationcell activationimmune effector processnitrogen compound metabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processcatabolic processimmune responseestablishment of localizationcell activationimmune effector processnitrogen compound metabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processcatabolic processimmune responseestablishment of localizationcell activationimmune effector processnitrogen comnitrogen compound metabolic processcellular metcellular metabolic processprimary metaprimary metabolic processsmall molecusmall molecule metabolic processorganic subsorganic substance metabolic processbiosyntheticbiosynthetic processcatabolic prcatabolic processimmune respoimmune responseestablishmenestablishment of localizationcell activatcell activationimmune effecimmune effector process
lyase activitylyase activitylyase activitylyase activitylyase activitylyase activitylyase activitylyase activitylyase activitylyase activitylyase activitylyase activity
extracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regionextracellular regioncellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0006098 pentose-phosphate shunt TAS
 biological_processGO:0009264 deoxyribonucleotide catabolic process IEA
 biological_processGO:0016052 carbohydrate catabolic process IBA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0046121 deoxyribonucleoside catabolic process IDA
 biological_processGO:0046386 deoxyribose phosphate catabolic process IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0034774 secretory granule lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:1904813 ficolin-1-rich granule lumen TAS
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004139 deoxyribose-phosphate aldolase activity IEA
 molecular_functionGO:0016829 lyase activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Pentose phosphate pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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