ENSG00000030419


Homo sapiens

Features
Gene ID: ENSG00000030419
  
Biological name :IKZF2
  
Synonyms : IKAROS family zinc finger 2 / IKZF2 / Q9UKS7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q34
Gene start: 212999691
Gene end: 213152427
  
Corresponding Affymetrix probe sets: 1555060_a_at (Human Genome U133 Plus 2.0 Array)   220567_at (Human Genome U133 Plus 2.0 Array)   231929_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000396253
Ensembl peptide - ENSP00000395203
Ensembl peptide - ENSP00000402132
Ensembl peptide - ENSP00000413680
Ensembl peptide - ENSP00000412869
Ensembl peptide - ENSP00000411444
Ensembl peptide - ENSP00000410447
Ensembl peptide - ENSP00000406783
Ensembl peptide - ENSP00000342876
Ensembl peptide - ENSP00000363439
Ensembl peptide - ENSP00000363446
Ensembl peptide - ENSP00000389548
Ensembl peptide - ENSP00000390045
NCBI entrez gene - 22807     See in Manteia.
OMIM - 606234
RefSeq - XM_017003592
RefSeq - XM_011510814
RefSeq - XM_011510815
RefSeq - XM_011510816
RefSeq - XM_011510817
RefSeq - XM_011510818
RefSeq - XM_011510819
RefSeq - XM_017003589
RefSeq - XM_017003590
RefSeq - XM_017003591
RefSeq - NM_001079526
RefSeq - NM_016260
RefSeq - XM_005246384
RefSeq - XM_005246385
RefSeq - XM_005246386
RefSeq - XM_011510802
RefSeq - XM_011510803
RefSeq - XM_011510804
RefSeq - XM_011510805
RefSeq - XM_011510807
RefSeq - XM_011510808
RefSeq - XM_011510809
RefSeq - XM_011510810
RefSeq - XM_011510811
RefSeq - XM_011510812
RefSeq Peptide - NP_001072994
RefSeq Peptide - NP_057344
swissprot - E7EPU0
swissprot - B4DWF2
swissprot - E7EUI1
swissprot - Q9UKS7
swissprot - A0A0A0MSL2
swissprot - A0A0A0MT14
swissprot - E7ES26
Ensembl - ENSG00000030419
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IKZF2ENSDARG00000069111Danio rerio
 IKZF2ENSGALG00000003136Gallus gallus
 Ikzf2ENSMUSG00000025997Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IKZF4 / Q9H2S9 / IKAROS family zinc finger 4ENSG0000012341155
IKZF1 / Q13422 / IKAROS family zinc finger 1ENSG0000018581150
IKZF3 / Q9UKT9 / IKAROS family zinc finger 3ENSG0000016140546
IKZF5 / Q9H5V7 / IKAROS family zinc finger 5ENSG0000009557419


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR026939  At2g23090-like
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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