ENSG00000039987


Homo sapiens

Features
Gene ID: ENSG00000039987
  
Biological name :BEST2
  
Synonyms : BEST2 / bestrophin 2 / Q8NFU1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.13
Gene start: 12751702
Gene end: 12758458
  
Corresponding Affymetrix probe sets: 207432_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000448310
Ensembl peptide - ENSP00000449403
Ensembl peptide - ENSP00000042931
Ensembl peptide - ENSP00000447203
NCBI entrez gene - 54831     See in Manteia.
OMIM - 607335
RefSeq - NM_017682
RefSeq - XM_005259963
RefSeq Peptide - NP_060152
swissprot - H0YIH1
swissprot - Q8NFU1
Ensembl - ENSG00000039987
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 best2ENSDARG00000079163Danio rerio
 Best2ENSMUSG00000052819Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BEST3 / Q8N1M1 / bestrophin 3ENSG0000012732553
BEST4 / Q8NFU0 / bestrophin 4ENSG0000014295953
BEST1 / O76090 / bestrophin 1ENSG0000016799544


Protein motifs (from Interpro)
Interpro ID Name
 IPR000615  Bestrophin
 IPR021134  Bestrophin/UPF0187


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006821 chloride transport IEA
 biological_processGO:0007608 sensory perception of smell ISS
 biological_processGO:0008150 biological_process ND
 biological_processGO:0051899 membrane depolarization ISS
 biological_processGO:1902476 chloride transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005929 cilium ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0034707 chloride channel complex ISS
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005254 chloride channel activity ISS


Pathways (from Reactome)
Pathway description
Stimuli-sensing channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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