ENSG00000054219


Homo sapiens

Features
Gene ID: ENSG00000054219
  
Biological name :LY75
  
Synonyms : LY75 / lymphocyte antigen 75 / O60449
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q24.2
Gene start: 159803355
Gene end: 159904749
  
Corresponding Affymetrix probe sets: 205668_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000263636
NCBI entrez gene - 4065     See in Manteia.
OMIM - 604524
RefSeq - NM_002349
RefSeq Peptide - NP_002340
swissprot - O60449
Ensembl - ENSG00000054219
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ly75ENSDARG00000053113Danio rerio
 LY75ENSGALG00000011153Gallus gallus
 Ly75ENSMUSG00000026980Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LY75-CD302 / LY75-CD302 readthroughENSG0000024867298
PLA2R1 / Q13018 / phospholipase A2 receptor 1ENSG0000015324629
MRC2 / Q9UBG0 / mannose receptor C type 2ENSG0000001102826
MRC1 / P22897 / mannose receptor C-type 1ENSG0000026031423


Protein motifs (from Interpro)
Interpro ID Name
 IPR000562  Fibronectin type II domain
 IPR000772  Ricin B, lectin domain
 IPR001304  C-type lectin-like
 IPR013806  Kringle-like fold
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018378  C-type lectin, conserved site
 IPR035992  Ricin B-like lectins
 IPR036943  Fibronectin type II domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0006954 inflammatory response TAS
 biological_processGO:0006955 immune response TAS
 biological_processGO:0007165 signal transduction IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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