ENSG00000058600


Homo sapiens

Features
Gene ID: ENSG00000058600
  
Biological name :POLR3E
  
Synonyms : POLR3E / Q9NVU0 / RNA polymerase III subunit E
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p12.2
Gene start: 22297375
Gene end: 22335103
  
Corresponding Affymetrix probe sets: 218016_s_at (Human Genome U133 Plus 2.0 Array)   222490_at (Human Genome U133 Plus 2.0 Array)   233458_at (Human Genome U133 Plus 2.0 Array)   233459_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000456967
Ensembl peptide - ENSP00000456718
Ensembl peptide - ENSP00000456771
Ensembl peptide - ENSP00000484648
Ensembl peptide - ENSP00000299853
Ensembl peptide - ENSP00000352140
Ensembl peptide - ENSP00000399254
Ensembl peptide - ENSP00000454225
Ensembl peptide - ENSP00000454507
Ensembl peptide - ENSP00000454875
Ensembl peptide - ENSP00000456454
Ensembl peptide - ENSP00000456526
NCBI entrez gene - 55718     See in Manteia.
NCBI entrez gene - 101060521     See in Manteia.
OMIM - 617815
RefSeq - XM_017023443
RefSeq - NM_001258033
RefSeq - NM_001258034
RefSeq - NM_001258035
RefSeq - NM_001258036
RefSeq - NM_018119
RefSeq - XM_006721063
RefSeq - XM_011545892
RefSeq - XM_011545893
RefSeq Peptide - NP_001244965
RefSeq Peptide - NP_060589
RefSeq Peptide - NP_001244962
RefSeq Peptide - NP_001244963
RefSeq Peptide - NP_001244964
swissprot - H3BSM3
swissprot - H3BM46
swissprot - H3BMR4
swissprot - H3BNJ0
swissprot - H3BRY1
swissprot - H3BS41
swissprot - Q9NVU0
swissprot - A0A0C4DH01
swissprot - H3BSI5
Ensembl - ENSG00000058600
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 polr3eENSDARG00000037358Danio rerio
 POLR3EENSGALG00000007008Gallus gallus
 Polr3eENSMUSG00000030880Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006886  DNA-directed RNA polymerase III subunit Rpc5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006383 transcription by RNA polymerase III IEA
 biological_processGO:0032481 positive regulation of type I interferon production TAS
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0051607 defense response to virus IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005666 DNA-directed RNA polymerase III complex IDA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0001056 RNA polymerase III activity IBA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity IEA


Pathways (from Reactome)
Pathway description
Cytosolic sensors of pathogen-associated DNA
RNA Polymerase III Chain Elongation
RNA Polymerase III Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000168495 P05423 / POLR3D / RNA polymerase III subunit D  / complex






 

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contact: otassy@igbmc.fr