ENSG00000069535


Homo sapiens

Features
Gene ID: ENSG00000069535
  
Biological name :MAOB
  
Synonyms : MAOB / monoamine oxidase B / P27338
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: p11.3
Gene start: 43766611
Gene end: 43882447
  
Corresponding Affymetrix probe sets: 1561009_at (Human Genome U133 Plus 2.0 Array)   1561010_a_at (Human Genome U133 Plus 2.0 Array)   204041_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000367309
NCBI entrez gene - 4129     See in Manteia.
OMIM - 309860
RefSeq - XM_017029524
RefSeq - NM_000898
RefSeq - XM_005272608
RefSeq - XM_017029523
RefSeq Peptide - NP_000889
swissprot - P27338
Ensembl - ENSG00000069535
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 maoENSDARG00000023712Danio rerio
 MAOBENSGALG00000032836Gallus gallus
 MaobENSMUSG00000040147Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAOA / P21397 / monoamine oxidase AENSG0000018922172


Protein motifs (from Interpro)
Interpro ID Name
 IPR001613  Flavin amine oxidase
 IPR002937  Amine oxidase
 IPR036188  FAD/NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009636 response to toxic substance IEA
 biological_processGO:0010044 response to aluminum ion IEA
 biological_processGO:0010269 response to selenium ion IEA
 biological_processGO:0014063 negative regulation of serotonin secretion IEA
 biological_processGO:0021762 substantia nigra development HEP
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0042135 neurotransmitter catabolic process IEA
 biological_processGO:0042420 dopamine catabolic process TAS
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0045964 positive regulation of dopamine metabolic process IEA
 biological_processGO:0048545 response to steroid hormone IEA
 biological_processGO:0050665 hydrogen peroxide biosynthetic process NAS
 biological_processGO:0051412 response to corticosterone IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005740 mitochondrial envelope TAS
 cellular_componentGO:0005741 mitochondrial outer membrane TAS
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0008131 primary amine oxidase activity IEA
 molecular_functionGO:0009055 electron transfer activity TAS
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA


Pathways (from Reactome)
Pathway description
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr