ENSG00000073350


Homo sapiens

Features
Gene ID: ENSG00000073350
  
Biological name :LLGL2
  
Synonyms : LLGL2 / LLGL2, scribble cell polarity complex component / Q6P1M3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q25.1
Gene start: 75525080
Gene end: 75575208
  
Corresponding Affymetrix probe sets: 1554006_a_at (Human Genome U133 Plus 2.0 Array)   203713_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464603
Ensembl peptide - ENSP00000167462
Ensembl peptide - ENSP00000364375
Ensembl peptide - ENSP00000376333
Ensembl peptide - ENSP00000461953
Ensembl peptide - ENSP00000462439
Ensembl peptide - ENSP00000463150
Ensembl peptide - ENSP00000463390
Ensembl peptide - ENSP00000463501
Ensembl peptide - ENSP00000463721
Ensembl peptide - ENSP00000464397
Ensembl peptide - ENSP00000464451
Ensembl peptide - ENSP00000464483
Ensembl peptide - ENSP00000464598
NCBI entrez gene - 3993     See in Manteia.
RefSeq - XM_017024632
RefSeq - NM_001015002
RefSeq - NM_001031803
RefSeq - NM_004524
RefSeq - XM_011524801
RefSeq - XM_011524802
RefSeq - XM_011524807
RefSeq - XM_017024625
RefSeq - XM_017024626
RefSeq - XM_017024627
RefSeq - XM_017024628
RefSeq - XM_017024629
RefSeq - XM_017024630
RefSeq - XM_017024631
RefSeq Peptide - NP_001026973
RefSeq Peptide - NP_004515
RefSeq Peptide - NP_001015002
swissprot - J3QL58
swissprot - J3QLD8
swissprot - J3QLV4
swissprot - J3QRV5
swissprot - J3QRZ8
swissprot - J3QS20
swissprot - J3QSA6
swissprot - J3KRE1
swissprot - Q6P1M3
swissprot - J3KSD5
swissprot - J3QKM6
Ensembl - ENSG00000073350
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 llgl2ENSDARG00000023920Danio rerio
 LLGL2ENSGALG00000008057Gallus gallus
 Llgl2ENSMUSG00000020782Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LLGL1 / Q15334 / LLGL1, scribble cell polarity complex componentENSG0000013189956
Q9Y2K9 / STXBP5L / syntaxin binding protein 5 likeENSG0000014508729
Q5T5C0 / STXBP5 / syntaxin binding protein 5ENSG0000016450629


Protein motifs (from Interpro)
Interpro ID Name
 IPR000664  Lethal(2) giant larvae protein
 IPR001680  WD40 repeat
 IPR013577  Lethal giant larvae homologue 2
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006887 exocytosis IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0017157 regulation of exocytosis IBA
 biological_processGO:0032878 regulation of establishment or maintenance of cell polarity IDA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0050708 regulation of protein secretion IBA
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017137 Rab GTPase binding IBA
 molecular_functionGO:0030165 PDZ domain binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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